4.7 Article

Responses of Ruditapes philippinarum to contamination by pharmaceutical drugs under ocean acidification scenario

Related references

Note: Only part of the references are listed.
Article Marine & Freshwater Biology

Can ocean warming alter sub-lethal effects of antiepileptic and antihistaminic pharmaceuticals in marine bivalves?

Angela Almeida et al.

Summary: This study evaluated the impacts of ocean warming on two pharmaceutical drugs, Carbamazepine and Cetirizine, in the edible clam Ruditapes philippinarum. The results showed limited effects of the drugs at control and warming conditions, with warming improving the oxidative status of contaminated clams, especially when both drugs were combined. Defense mechanisms were activated under higher stress levels, highlighting the need for further research on this topic due to increasing marine heat waves and pollution levels.

AQUATIC TOXICOLOGY (2021)

Article Environmental Sciences

Environmental pharmaceuticals and climate change: The case study of carbamazepine in M. galloprovincialis under ocean acidification scenario

Marica Mezzelani et al.

Summary: The study found that under simulated ocean acidification scenarios, the interaction between carbamazepine and acidification can increase cellular hazard in marine organisms.

ENVIRONMENT INTERNATIONAL (2021)

Article Environmental Sciences

Near future ocean acidification modulates the physiological impact of fluoxetine at environmental concentration on larval urchins

Hau Kwan Abby Lo et al.

Summary: The study found that the impacts of pharmaceutical discharge on aquatic systems interact with environmental conditions, such as ocean acidification, affecting the physiology, behavior, and DNA integrity of sea urchin larvae. Under reduced pH conditions, the negative impacts of fluoxetine exposure were attenuated, resulting in lower levels of DNA damage compared to ambient pH conditions. Antagonistic interactions were observed, with larvae exposed to both reduced pH and fluoxetine exhibiting better performance than those exposed to only one stressor.

SCIENCE OF THE TOTAL ENVIRONMENT (2021)

Article Environmental Sciences

Effects of temperature on caffeine and carbon nanotubes co-exposure in Ruditapes philippinarum

Raffaele Piscopo et al.

Summary: In this study, the effects of caffeine and functionalized multi-walled carbon nanotubes on clams were evaluated at different temperature levels. The results showed negative impact of these compounds at the control temperature, with a decrease in protein content and metabolism. The biotransformation capacity at 18 degrees Celsius may explain the lower caffeine concentration observed and differences among treatments were less evident at the increased temperature level.

CHEMOSPHERE (2021)

Review Environmental Sciences

Occurrence of the antiepileptic carbamazepine in water and bivalves from marine environments: A review

Angela Almeida et al.

Summary: Pharmaceutical drugs have been shown to negatively impact aquatic organisms, with Carbamazepine (CBZ) found in marine environments at concentrations up to 1 μg/L and in marine bivalves up to 13 ng/g dry weight. Bivalves are good bioindicators for monitoring environmental pollution in marine ecosystems.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2021)

Review Geochemistry & Geophysics

Ocean Acidification and Coastal Marine Invertebrates: Tracking CO2 Effects from Seawater to the Cell

Frank Melzner et al.

ANNUAL REVIEW OF MARINE SCIENCE, VOL 12 (2020)

Article Environmental Sciences

The influence of climate change related factors on the response of two clam species to diclofenac

Silvana Costa et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2020)

Article Environmental Sciences

Distribution of micropollutants in estuarine and sea water along the Portuguese coast

Joao C. G. Sousa et al.

MARINE POLLUTION BULLETIN (2020)

Article Engineering, Marine

Exposure to Decreased pH and Caffeine Affects Hemocyte Parameters in the Mussel Mytilus galloprovincialis

Marco Munari et al.

JOURNAL OF MARINE SCIENCE AND ENGINEERING (2020)

Article Environmental Sciences

Effects of pH on salicylic acid toxicity in terms of biomarkers determined in the marine gastropod Gibbula umbilicalis

Ricardo Dionisio et al.

MARINE ENVIRONMENTAL RESEARCH (2020)

Article Environmental Sciences

Human pharmaceuticals in marine mussels: Evidence of sneaky environmental hazard along Italian coasts

Marica Mezzelani et al.

MARINE ENVIRONMENTAL RESEARCH (2020)

Article Environmental Sciences

Effects of single and combined exposure to cocaine and benzoylecgonine on the oxidative status of Mytilus galloprovincialis

Beatrice De Felice et al.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2020)

Review Chemistry, Multidisciplinary

Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods

Manvendra Patel et al.

CHEMICAL REVIEWS (2019)

Article Environmental Sciences

Pharmaceuticals as chemical markers of wastewater contamination in the vulnerable area of the Ebro Delta (Spain)

Mira Celic et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2019)

Article Environmental Sciences

Stress responses in Crassostrea gasar exposed to combined effects of acute pH changes and phenanthrene

Daina Lima et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2019)

Article Marine & Freshwater Biology

Oxidative and interactive challenge of cadmium and ocean acidification on the smooth scallop Flexopecten glaber

Alessandro Nardi et al.

AQUATIC TOXICOLOGY (2018)

Article Environmental Sciences

Ecotoxicity of the antihistaminic drug cetirizine to Ruditapes philippinarum clams

Angela Almeida et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2017)

Article Engineering, Environmental

Toxic effects of the antihistamine cetirizine in mussel Mytilus galloprovincialis

Miguel Teixeira et al.

WATER RESEARCH (2017)

Review Environmental Sciences

HUMAN PHARMACEUTICALS IN THE MARINE ENVIRONMENT: FOCUS ON EXPOSURE AND BIOLOGICAL EFFECTS IN ANIMAL SPECIES

Elena Fabbri et al.

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2016)

Article Environmental Sciences

General stress, detoxification pathways, neurotoxicity and genotoxicity evaluated in Ruditapes philippinarum exposed to human pharmaceuticals

Gabriela V. Aguirre-Martinez et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2016)

Article Marine & Freshwater Biology

Presence of the pharmaceutical drug carbamazepine in coastal systems: Effects on bivalves

Angela Almeida et al.

AQUATIC TOXICOLOGY (2014)

Article Environmental Sciences

Polar organic micropollutants in the coastal environment of different marine systems

Karsten Noedler et al.

MARINE POLLUTION BULLETIN (2014)

Article Biochemical Research Methods

Monitoring carbamazepine in surface and wastewaters by an immunoassay based on a monoclonal antibody

Arnold Bahlmann et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2009)

Article Pharmacology & Pharmacy

Appropriate calibration curve fitting in ligand binding assays

John W. A. Findlay et al.

AAPS JOURNAL (2007)