Autoimmune disease and COVID-19: a multicentre observational study in the United Kingdom

Article Hematology

Clinical outcomes and the impact of prior oral anticoagulant use in patients with coronavirus disease 2019 admitted to hospitals in the UK - a multicentre observational study

Deepa J. Arachchillage et al.

Summary: Coagulation dysfunction and thrombosis are common complications in COVID-19 patients. this study found that prior use of oral anticoagulants may lead to better outcomes, including reducing the likelihood of admission to the ICU.

BRITISH JOURNAL OF HAEMATOLOGY (2022)

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Review Rheumatology

Prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases: a systematic review and meta-analysis

Shintaro Akiyama et al.

Summary: Patients with autoimmune diseases have a higher risk of COVID-19, primarily due to glucocorticoid use. Monotherapy with b/tsDMARDs is associated with a lower risk of hospitalisation and death.

ANNALS OF THE RHEUMATIC DISEASES (2021)

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Article Immunology

Short term outcomes of COVID-19 in lupus: Propensity score matched analysis from a nationwide multi-centric research network

Rahul Raiker et al.

Summary: Individuals with lupus who contracted COVID-19 had comparable mortality but higher risks of hospitalization, ICU admission, mechanical ventilation, stroke, VTE, and sepsis compared to the general population. Factors such as gender, race, presence of nephritis, and use of immunomodulators were associated with COVID-19 outcomes.

JOURNAL OF AUTOIMMUNITY (2021)

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Review Rheumatology

Antiphospholipid antibodies in COVID-19: a meta-analysis and systematic review

Muhanad Taha et al.

Summary: aPLs were detected in nearly half of patients with COVID-19, and higher prevalence of aPL was found in severe disease. However, there was no association between aPL positivity and disease outcomes including thrombosis, invasive ventilation and mortality. Further studies are required to identify the clinical and pathological role of aPL in COVID-19.

RMD OPEN (2021)

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Article Rheumatology