4.6 Article

Effectiveness of NLRP3 Inhibitor as a Non-Hormonal Treatment for ovarian endometriosis

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Inhibition of the NLRP3 inflammasome prevents ovarian aging

Jose M. Navarro-Pando et al.

Summary: The study demonstrates that the NLRP3 inflammasome plays a crucial role in ovarian aging and female fertility, showing potential as a new therapeutic target for infertility treatment.

SCIENCE ADVANCES (2021)

Article Cell Biology

E3 ubiquitin ligase TRIM24 deficiency promotes NLRP3/caspase-1/IL-1β-mediated pyroptosis in endometriosis

Yuanyuan Hang et al.

Summary: The study revealed that TRIM24 is downregulated in endometriosis and may participate in the progression of the disease by inhibiting the NLRP3/caspase-1/IL-1 beta-mediated pyroptotic pathway and cell migration. The findings suggest a significant molecular mechanism underlying endometriosis.

CELL BIOLOGY INTERNATIONAL (2021)

Review Pharmacology & Pharmacy

Pharmacological Inhibition of the Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome with MCC950

Sarah E. Corcoran et al.

Summary: Activation of the NLRP3 inflammasome can lead to inflammatory responses and cell death, and is associated with various diseases. Inhibitors of NLRP3 have potential clinical value in preventing the harmful effects of NLRP3 activation on human diseases.

PHARMACOLOGICAL REVIEWS (2021)

Article Biochemistry & Molecular Biology

Novel ovarian endometriosis model causes infertility via iron-mediated oxidative stress in mice

Shotaro Hayashi et al.

REDOX BIOLOGY (2020)

Review Medicine, General & Internal

Laparoscopic surgery for endometriosis

Celine Bafort et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2020)

Article Cell Biology

Macrophage Immune Memory Controls Endometriosis in Mice and Humans

Mohamed Jeljeli et al.

CELL REPORTS (2020)

Review Biochemistry & Molecular Biology

NOD-like receptors and inflammasomes: A review of their canonical and non-canonical signaling pathways

Jaye M. Platnich et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2019)

Review Endocrinology & Metabolism

Endometriosis

Serdar E. Bulun et al.

ENDOCRINE REVIEWS (2019)

Article Radiology, Nuclear Medicine & Medical Imaging

Transvaginal US of Endometriosis: Looking Beyond the Endometrioma with a Dedicated Protocol

Belinda G. Collins et al.

RADIOGRAPHICS (2019)

Review Immunology

Pharmacological Inhibitors of the NLRP3 Inflammasome

Ayesha Zahid et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Obstetrics & Gynecology

Risk for and consequences of endometriosis: A critical epidemiologic review

A. L. Shafrir et al.

BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY (2018)

Article Biochemistry & Molecular Biology

Nobiletin alleviates endometriosis via down-regulating NF-κB activity in endometriosis mouse model

Xin Wei et al.

BIOSCIENCE REPORTS (2018)

Article Medicine, Research & Experimental

Tranilast directly targets NLRP3 to treat inflammasome-driven diseases

Yi Huang et al.

EMBO MOLECULAR MEDICINE (2018)

Review Biotechnology & Applied Microbiology

Targeting the NLRP3 inflammasome in inflammatory diseases

Matthew S. J. Mangan et al.

NATURE REVIEWS DRUG DISCOVERY (2018)

Article Medicine, General & Internal

Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes

F. De Benedetti et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Endometriosis

Krina T. Zondervan et al.

NATURE REVIEWS DISEASE PRIMERS (2018)

Review Immunology

Mechanisms governing inflammasome activation, assembly and pyroptosis induction

Sannula Kesavardhana et al.

INTERNATIONAL IMMUNOLOGY (2017)

Review Pharmacology & Pharmacy

Inflammasome as a Key Pathogenic Mechanism in Endometriosis

Pedro Bullon et al.

CURRENT DRUG TARGETS (2017)

Article Immunology

Homeostasis-altering molecular processes as mechanisms of inflammasome activation

Adrian Liston et al.

NATURE REVIEWS IMMUNOLOGY (2017)

Article Biochemistry & Molecular Biology

Non-thermal plasma prevents progression of endometriosis in mice

Chiharu Ishida et al.

FREE RADICAL RESEARCH (2016)

Article Medical Laboratory Technology

Association of the Precursor of Interleukin-1 and Peritoneal InflammationRole in Pathogenesis of Endometriosis

Justyna Sikora et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2016)

Review Biochemistry & Molecular Biology

Mechanism and Regulation of NLRP3 Inflammasome Activation

Yuan He et al.

TRENDS IN BIOCHEMICAL SCIENCES (2016)

Review Obstetrics & Gynecology

Prevention of the recurrence of symptom and lesions after conservative surgery for endometriosis

Kaori Koga et al.

FERTILITY AND STERILITY (2015)

Article Biochemistry & Molecular Biology

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Rebecca C. Coll et al.

NATURE MEDICINE (2015)

Article Obstetrics & Gynecology

ESHRE guideline: management of women with endometriosis

G. A. J. Dunselman et al.

HUMAN REPRODUCTION (2014)

Article Obstetrics & Gynecology

Association of History of Surgery for Endometriosis With Severity of Deeply Infiltrating Endometriosis

Jeanne Sibiude et al.

OBSTETRICS AND GYNECOLOGY (2014)

Review Multidisciplinary Sciences

Inflammasomes in health and disease

Till Strowig et al.

NATURE (2012)

Review Medicine, General & Internal

Endometriosis and infertility: pathophysiology and management

Dominique de Ziegler et al.

LANCET (2010)

Review Obstetrics & Gynecology

Recurrence of endometriosis and its control

Sun-Wei Guo

HUMAN REPRODUCTION UPDATE (2009)

Article Obstetrics & Gynecology

Interleukin 1β, interleukin-6, and tumor necrosis factor-α in endometriotic tissue and in endometrium

A Bergqvist et al.

FERTILITY AND STERILITY (2001)