Journal
RADIATION MEASUREMENTS
Volume 152, Issue -, Pages -Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.radmeas.2022.106721
Keywords
Optically stimulated luminescence; Proton therapy; Ionization quenching; MgB4O (7)
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Funding
- Alexander von Humboldt Research Fellowship for Experience Researchers
- US National Science Foundation [OCI-1126330]
- Swiss National Science Foundation [206021 177028]
- Swiss National Science Foundation (SNF) [206021_177028] Funding Source: Swiss National Science Foundation (SNF)
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The objective of this study is to demonstrate that MgB4O7:Ce,Li, a new OSL dosimetric material, has improved response for proton therapy dosimetry and shows less reduction in luminescence detector efficiency with particle linear energy transfer (LET).
The objective of this work is to demonstrate that MgB4O7:Ce,Li, a new optically stimulated luminescence (OSL) dosimetric material, shows improved response for proton therapy dosimetry, with less reduction in luminescence detector efficiency with the particle linear energy transfer (LET). MgB4O7:Ce,Li was synthesized and its luminescence efficiency as a function of LET was characterized for dose-averaged LET values from 0.73 keV/mu m up to 74.9 keV/mu m using proton, He-4, and C-12 ion beams. Commercial Al2O3:C OSLDs were also used for comparison. Monte Carlo simulations were used to predict the material's response in pristine and spread-out Bragg peaks (SOBP), suggesting the MgB4O7:Ce,Li would offer minimum quenching in proton beams of energies relevant to radiotherapy. This prediction was confirmed by irradiations of MgB4O7:Ce,Li and Al2O3:C along SOBPs from proton beams. The results demonstrate that new OSL materials optimized for proton dosimetry can be developed using their dose response to low-LET radiation as a guide during material development.
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