Journal
PROGRESS IN ORGANIC COATINGS
Volume 166, Issue -, Pages -Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.porgcoat.2022.106796
Keywords
Poly(methyl methacrylate); Poly(2-ethyl-2-oxazoline); Tea polyphenol; Grafting technology; Protein antifouling property
Funding
- Japan Society for the Promotion of Science (JSPS) KAKENHI [19H02778, 20H02797, 20K15343]
Ask authors/readers for more resources
This study focuses on the application of bio-based materials in the synthesis of functional films, and demonstrates that the PEtOx-GA-PEI-S functional film is a promising material for biomedical anti-fouling applications.
Studies of antifouling materials have been focused on substituting synthetic materials with bio-based materials, which are essentially derived from plants and suitably categorized as 'green' and renewable materials. Gallic acid (GA), which exists abundantly in tea and other plants, has important biological and pharmacological properties. In this study, GA was used as a linker molecule to combine poly(2-ethyl-2-oxazoline) (PEtOx) and poly(methyl methacrylate) (PMMA). Firstly, bio-based polymer (PEtOx-GA) was synthesized and then was reacted with the poly(ethyleneimine)-modified PMMA substrate (PEI-S) to form the functional film (PEtOx-GA-PEI-S) via Schiff base and Michael addition reactions. The PEtOx-GA-PEI-S functional film prevented protein adsorption, as demonstrated by water contact angle testing and an adsorption experiment with bovine serum albumin (BSA) protein, and the mass of adsorbed BSA was reduced by ~70%. This study focuses on the recent developments with bio-based materials that are employed for functional film synthesis and indicate that PEtOx-GA-PEI-S functional film is a highly promising candidate for biomedical antifouling applications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available