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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2015)
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Peter Bretscher et al.
EMBO MOLECULAR MEDICINE (2015)
The fatty acid desaturase 2 (FADS2) gene product catalyzes Δ4 desaturation to yield n-3 docosahexaenoic acid and n-6 docosapentaenoic acid in human cells
Hui Gyu Park et al.
FASEB JOURNAL (2015)
Nonenzymatic lipid mediators, neuroprostanes, exert the antiarrhythmic properties of docosahexaenoic acid
Jerome Roy et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
15-Hydroxyprostaglandin Dehydrogenase Generation of Electrophilic Lipid Signaling Mediators from Hydroxy Ω-3 Fatty Acids
Stacy Gelhaus Wendell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections
Jesmond Dalli et al.
NATURE MEDICINE (2015)
Astrocytes show reduced support of motor neurons with aging that is accelerated in a rodent model of ALS
Melanie M. Das et al.
NEUROBIOLOGY OF AGING (2015)
Resolvin Infectious Inflammation by Targeting the Host Response
Craig R. Lee et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival
Dennis S. Rice et al.
NATURE COMMUNICATIONS (2015)
Advances in Our Understanding of Oxylipins Derived from Dietary PUFAs
Melissa Gabbs et al.
ADVANCES IN NUTRITION (2015)
Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue
Romain A. Colas et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2014)
Pathophysiology of isoprostanes in the cardiovascular system: implications of isoprostane-mediated thromboxane A2 receptor activation
Jochen Bauer et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects
Mark M. Yore et al.
CELL (2014)
Pro-resolving lipid mediators are leads for resolution physiology
Charles N. Serhan
NATURE (2014)
Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis
Phillip J. White et al.
NATURE MEDICINE (2014)
Role of the Non-enzymatic Metabolite of Eicosapentaenoic Acid, 5-epi-5-F3t-Isoprostane in the Regulation of [3H]D-Aspartate Release in Isolated Bovine Retina
Jamal Jamil et al.
NEUROCHEMICAL RESEARCH (2014)
Lipid Profiling following Intake of the Omega 3 Fatty Acid DHA Identifies the Peroxidized Metabolites F4-Neuroprostanes as the Best Predictors of Atherosclerosis Prevention
Cecile Gladine et al.
PLOS ONE (2014)
Generation and Dietary Modulation of Anti-Inflammatory Electrophilic Omega-3 Fatty Acid Derivatives
Chiara Cipollina et al.
PLOS ONE (2014)
Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages
Bin Deng et al.
PLOS ONE (2014)
Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection
Jesmond Dalli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
COX-2-derived endocannabinoid metabolites as novel inflammatory mediators
Mireille Alhouayek et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
Protection after stroke: cellular effectors of neurovascular unit integrity
Rafael Andres Posada-Duque et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms
Mohammad Alsalem et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza
Masayuki Morita et al.
CELL (2013)
Fatty acid analysis by high resolution gas chromatography and mass spectrometry for clinical and experimental applications
J. Thomas Brenna
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2013)
Novel n-3 Immunoresolvents: Structures and Actions
Jesmond Dalli et al.
SCIENTIFIC REPORTS (2013)
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Vahid Farrokhi et al.
CLINICAL & TRANSLATIONAL IMMUNOLOGY (2013)
Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke
Nicolas G. Bazan et al.
EXPERIMENTAL NEUROLOGY (2012)
Expanding the horizons of lipidomics. Towards fluxolipidomics
Michel Lagarde et al.
MOLECULAR MEMBRANE BIOLOGY (2012)
Maintenance of Arachidonic Acid and Evidence of Δ5 Desaturation in Cats Fed γ-Linolenic and Linoleic Acid Enriched Diets
Luciano Trevizan et al.
LIPIDS (2012)
Infection regulates pro-resolving mediators that lower antibiotic requirements
Nan Chiang et al.
NATURE (2012)
Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans
Christopher E. Ramsden et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2012)
Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century
Tanya L. Blasbalg et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2011)
Recessive Mutations in ELOVL4 Cause Ichthyosis, Intellectual Disability, and Spastic Quadriplegia
Mohammed A. Aldahmesh et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
Docosahexaenoic Acid Signalolipidomics in Nutrition: Significance in Aging, Neuroinflammation, Macular Degeneration, Alzheimer's, and Other Neurodegenerative Diseases
Nicolas G. Bazan et al.
ANNUAL REVIEW OF NUTRITION, VOL 31 (2011)
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
Jesper Z. Haeggstrom et al.
CHEMICAL REVIEWS (2011)
Free Radical Lipid Peroxidation: Mechanisms and Analysis
Huiyong Yin et al.
CHEMICAL REVIEWS (2011)
Novel Proresolving Aspirin-Triggered DHA Pathway
Charles N. Serhan et al.
CHEMISTRY & BIOLOGY (2011)
Poxytrins, a class of oxygenated products from polyunsaturated fatty acids, potently inhibit blood platelet aggregation
Ping Chen et al.
FASEB JOURNAL (2011)
Lipoxygenases Mediate the Effect of Essential Fatty Acid in Skin Barrier Formation A PROPOSED ROLE IN RELEASING OMEGA-HYDROXYCERAMIDE FOR CONSTRUCTION OF THE CORNEOCYTE LIPID ENVELOPE
Yuxiang Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Controlling Herpes Simplex Virus-Induced Ocular Inflammatory Lesions with the Lipid-Derived Mediator Resolvin E1
Naveen K. Rajasagi et al.
JOURNAL OF IMMUNOLOGY (2011)
Nonenzymatic free radical-catalyzed generation of 15-deoxy-Delta(12,14)-prostaglandin J(2)-like compounds (deoxy-J(2)-isoprostanes) in vivo
Klarissa D. Hardy et al.
JOURNAL OF LIPID RESEARCH (2011)
The fatty acid oxidation product 15-A3t-Isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation
Joshua D. Brooks et al.
JOURNAL OF NEUROCHEMISTRY (2011)
DIFFERENTIAL EFFECT OF AMYLOID BETA ON THE CYTOCHROME P450 EPOXYGENASE ACTIVITY IN RAT BRAIN
P. Sarkar et al.
NEUROSCIENCE (2011)
Docosahexaenoic Acid-Derived Neuroprotectin D1 Induces Neuronal Survival via Secretase- and PPARγ-Mediated Mechanisms in Alzheimer's Disease Models
Yuhai Zhao et al.
PLOS ONE (2011)
FADS2 Function Loss at the Cancer Hotspot 11q13 Locus Diverts Lipid Signaling Precursor Synthesis to Unusual Eicosanoid Fatty Acids
Woo Jung Park et al.
PLOS ONE (2011)
Omega-3 fatty acid oxidation products prevent vascular endothelial cell activation by coplanar polychlorinated biphenyls
Zuzana Majkova et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2011)
Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium
Rozenn N. Lemaitre et al.
PLOS GENETICS (2011)
Very long chain sphingolipids: Tissue expression, function and synthesis
Roger Sandhoff
FEBS LETTERS (2010)
Structural Basis of Fatty Acid Substrate Binding to Cyclooxygenase-2
Alex J. Vecchio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein
Martin-Paul Agbaga et al.
JOURNAL OF LIPID RESEARCH (2010)
Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids
Alison L. Groeger et al.
NATURE CHEMICAL BIOLOGY (2010)
The Science of Stroke: Mechanisms in Search of Treatments
Michael A. Moskowitz et al.
NEURON (2010)
Cytochrome P450-dependent metabolism of omega-6 and omega-3 long-chain polyunsaturated fatty acids
Cosima Arnold et al.
PHARMACOLOGICAL REPORTS (2010)
Amino acid-containing membrane lipids in bacteria
Otto Geiger et al.
PROGRESS IN LIPID RESEARCH (2010)
Platelet function and Isoprostane biology. Should Isoprostanes be the newest member of the Orphan-ligand family?
Harold J. Ting et al.
JOURNAL OF BIOMEDICAL SCIENCE (2010)
ω-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study
John Paul SanGiovanni et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2009)
Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions
Charles N. Serhan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Cyclooxygenases: structural and functional insights
Carol A. Rouzer et al.
JOURNAL OF LIPID RESEARCH (2009)
Human tear film and meibum. Very long chain wax esters and (O-acyl)-omega-hydroxy fatty acids of meibum
Igor A. Butovich et al.
JOURNAL OF LIPID RESEARCH (2009)
An alternate pathway to long-chain polyunsaturates: the FADS2 gene product Δ8-desaturates 20:2n-6 and 20:3n-3
Woo Jung Park et al.
JOURNAL OF LIPID RESEARCH (2009)
Beyond prostaglandins - Chemistry and biology of cyclic oxygenated metabolites formed by free-radical pathways from polyunsaturated fatty acids
Urich Jahn et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Lipid Mediators in Health and Disease: Enzymes and Receptors as Therapeutic Targets for the Regulation of Immunity and Inflammation
Takao Shimizu
Annual Review of Pharmacology and Toxicology (2008)
Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus
C. N. Serhan et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the ω-3 polyunsaturated fatty acid docosahexaenoic acid
Erik S. Musiek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The identification of mono-, di-, tri-, and tetragalactosyl-diacylglycerols and their natural estolides in oat kernels
Robert A. Moreau et al.
LIPIDS (2008)
Principles of bioactive lipid signalling: lessons from sphingolipids
Yusuf A. Hannun et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
General detoxification and stress responses are mediated by oxidized lipids through TGA transcription factors in Arabidopsis
Stefan Mueller et al.
PLANT CELL (2008)
Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids
Martin-Paul Agbaga et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A Stargardt disease-3 mutation in the mouse Elovl4 gene causes retinal deficiency of C32-C36 acyl phosphatidylcholines
Anne McMahon et al.
FEBS LETTERS (2007)
Antiinflammatory effects of the cyclopentenone isoprostane 15-A2-IsoP in human gestational tissues
Martha Lappas et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Resolvin E1 and protectin D1 activate inflammation-resolution programmes
Jan M. Schwab et al.
NATURE (2007)
Resolution of inflammation: state of the art, definitions and terms
Charles N. Serhan et al.
FASEB JOURNAL (2007)
Urinary prostaglandin F2α is generated from the isoprostane pathway and not the cyclooxygenase in humans
Huiyong Yin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness
Bruce D. Levy et al.
JOURNAL OF IMMUNOLOGY (2007)
Resolution phase of inflammation: Novel endogenous anti-inflammatory and proresolving lipid mediators and pathways
Charles N. Serhan
ANNUAL REVIEW OF IMMUNOLOGY (2007)
Cardiovascular pharmacology and physiology of the isoprostanes
Jean-Luc Cracowski et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2006)
Brain elongation of linoleic acid is a negligible source of the arachidonate in brain phospholipids of adult rats
James C. DeMar et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2006)
Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: Assignments of dihydroxy-containing docosatrienes
CN Serhan et al.
JOURNAL OF IMMUNOLOGY (2006)
The isoprostanes - Unique products of arachidonate peroxidation: Their role as mediators of oxidant stress
JD Morrow
CURRENT PHARMACEUTICAL DESIGN (2006)
Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: Their role and involvement in neurological disorders
John W. Phillis et al.
BRAIN RESEARCH REVIEWS (2006)
Prostaglandin E-2 promotes degranulation-independent release of MCP-1 from mast cells
T Nakayama et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2006)
Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages
ES Musiek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease
WJ Lukiw et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Astrocytes in cerebral ischemic injury: Morphological and general considerations
KS Panickar et al.
GLIA (2005)
Biomarkers of oxidative stress study II.: Are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?
MB Kadiiska et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1
M Arita et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution
CN Serhan
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2005)
Isofurans: Novel products of lipid peroxidation that define the occurrence of oxidant injury in settings of elevated oxygen tension
JP Fessel et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
The pulmonary biology of isoprostanes
LJ Janssen
CHEMISTRY AND PHYSICS OF LIPIDS (2004)
Neuroprotectin D1: A docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress
PK Mukherjee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression
VL Marcheselli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Comparison of the properties of prostaglandin H synthase-1 and -2
RJ Kulmacz et al.
PROGRESS IN LIPID RESEARCH (2003)
Formation of prostaglandins E2 and D2 via the isoprostane pathway -: A mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase
L Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells -: Autacoids in anti-inflammation
S Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Studies towards the total synthesis of an epoxy isoprostane phospholipid, a potent activator of endothelial cells
ME Jung et al.
CHEMICAL COMMUNICATIONS (2003)
Resolvins: A family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
CN Serhan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Mayolenes:: Labile defensive lipids from the glandular hairs of a caterpillar (Pieris rapae)
SR Smedley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Leukotoxin-diol - A putative toxic mediator involved in acute respiratory distress syndrome
J Zheng et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2001)
A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy
K Zhang et al.
NATURE GENETICS (2001)
Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing
CN Serhan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
CDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family
A Marquardt et al.
GENOMICS (2000)