4.8 Article

Phenol-soluble modulins PSM alpha 3 and PSM beta 2 form nanotubes that are cross-alpha amyloids

Related references

Note: Only part of the references are listed.
Review Chemistry, Multidisciplinary

Cryo-EM of Helical Polymers

Fengbin Wang et al.

Summary: Cryo-EM is the preferred method for structural analysis of synthetic helical filaments, and it has revealed the enormous potential for polymorphism in self-assembled soft matter polymers. These structures have also highlighted the chaotic self-assembly behavior that makes it difficult to predict the structure of these polymers.

CHEMICAL REVIEWS (2022)

Article Multidisciplinary Sciences

The amphibian antimicrobial peptide uperin 3.5 is a cross-α/cross-β chameleon functional amyloid

Nir Salinas et al.

Summary: The study found that two subtypes of antimicrobial peptide uperin 3.5 can form functional amyloid fibrils, which has important physiological implications. Uperin 3.5 mainly forms cross-beta fibrils in the absence of lipids, but helical fibril formation is induced by bacterial cells or membrane mimetics, leading to membrane damage and cell death.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Article Multidisciplinary Sciences

Structural analysis of cross α-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials

Fengbin Wang et al.

Summary: The study describes a rational approach to design self-assembling peptide nanotubes based on lateral interactions between protofilaments with an unusual cross-alpha supramolecular architecture. Cryo-EM structural analysis reveals the designability of interfaces within the synthetic peptide assemblies and identifies a non-native structural interaction based on a pair of arginine residues, providing insights into the controlled structure of the resultant assemblies.

NATURE COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

Accurate prediction of protein structures and interactions using a three-track neural network

Minkyung Baek et al.

Summary: Through the three-track network, we achieved accuracies approaching those of DeepMind in CASP14, enabling rapid solution of challenging x-ray crystallography and cryo-electron microscopy structure modeling problems, and providing insights into the functions of proteins with currently unknown structure.

SCIENCE (2021)

Article Materials Science, Multidisciplinary

Deterministic chaos in the self-assembly of β sheet nanotubes from an amphipathic oligopeptide

Fengbin Wang et al.

Summary: Our study investigates the assembly of an octapeptide sequence and determines the atomic structure of the resulting fibrils using cryoelectron microscopy, revealing parallel and antiparallel beta sheets. The results demonstrate the chaotic nature of peptide self-assembly and underscore the importance of cryo-EM structural analysis for understanding these complex materials at near-atomic resolution.

MATTER (2021)

Review Chemistry, Multidisciplinary

Soft-Matter Nanotubes: A Platform for Diverse Functions and Applications

Toshimi Shimizu et al.

CHEMICAL REVIEWS (2020)

Article Biochemistry & Molecular Biology

Staphylococcus aureus PSMα3 Cross-α Fibril Polymorphism and Determinants of Cytotoxicity

Einav Tayeb-Fligelman et al.

STRUCTURE (2020)

Article Chemistry, Multidisciplinary

Controlled Lengthwise Assembly of Helical Peptide Nanofibers to Modulate CD8(+)T-Cell Responses

Chelsea N. Fries et al.

ADVANCED MATERIALS (2020)

Article Chemistry, Multidisciplinary

Artificial Intracellular Filaments

Zhaoqianqi Feng et al.

CELL REPORTS PHYSICAL SCIENCE (2020)

Article Chemistry, Multidisciplinary

Shape-Shifting Peptide Nanomaterials: Surface Asymmetry Enables pH-Dependent Formation and Interconversion of Collagen Tubes and Sheets

Andrea D. Merg et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Review Chemistry, Multidisciplinary

Half a century of amyloids: past, present and future

Pu Chun Ke et al.

CHEMICAL SOCIETY REVIEWS (2020)

Article Chemistry, Multidisciplinary

Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin α3 Toxicity

Zhihui Yao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Multidisciplinary Sciences

Ambidextrous helical nanotubes from self-assembly of designed helical hairpin motifs

Spencer A. Hughes et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Biochemical Research Methods

The de novo design of α-helical peptides for supramolecular self-assembly

Joseph L. Beesley et al.

CURRENT OPINION IN BIOTECHNOLOGY (2019)

Article Multidisciplinary Sciences

Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer's brain tissue

Marius Kollmer et al.

NATURE COMMUNICATIONS (2019)

Article Microbiology

Do amyloid structures formed by Staphylococcus aureus phenol-soluble modulins have a biological function?

Yue Zheng et al.

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2018)

Article Biochemistry & Molecular Biology

MolProbity: More and better reference data for improved all-atom structure validation

Christopher J. Williams et al.

PROTEIN SCIENCE (2018)

Review Chemistry, Multidisciplinary

Amyloid Polymorphism in the Protein Folding and Aggregation Energy Landscape

Jozef Adamcik et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Biochemistry & Molecular Biology

Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2

Elizabeth L. Guenther et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Article Chemistry, Multidisciplinary

Controlling the Diameters of Nanotubes Self-Assembled from Designed Peptide Bolaphiles

Yurong Zhao et al.

SMALL (2018)

Article Multidisciplinary Sciences

Physical basis of amyloid fibril polymorphism

William Close et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2

Elizabeth L. Guenther et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Designed peptides that assemble into cross-α amyloid-like structures

Shao-Qing Zhang et al.

NATURE CHEMICAL BIOLOGY (2018)

Article Multidisciplinary Sciences

Extreme amyloid polymorphism in Staphylococcus aureus virulent PSMα peptides

Nir Salinas et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Nanotubes, Plates, and Needles: Pathway-Dependent Self-Assembly of Computationally Designed Peptides

Yu Tian et al.

BIOMACROMOLECULES (2018)

Article Cell Biology

A microtubule bestiary: structural diversity in tubulin polymers

Sami Chaaban et al.

MOLECULAR BIOLOGY OF THE CELL (2017)

Letter Biochemical Research Methods

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

Shawn Q. Zheng et al.

NATURE METHODS (2017)

Article Multidisciplinary Sciences

The cytotoxic Staphylococcus aureus PSMαa3 reveals a cross-α amyloid-like fibril

Einav Tayeb-Fligelman et al.

SCIENCE (2017)

Article Biology

Discovery and design of self-assembling peptides

Shuguang Zhang

INTERFACE FOCUS (2017)

Article Materials Science, Biomaterials

A Supramolecular Vaccine Platform Based on α-Helical Peptide Nanofibers

Yaoying Wu et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)

Article Materials Science, Biomaterials

A Supramolecular Vaccine Platform Based on α-Helical Peptide Nanofibers

Yaoying Wu et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)

Review Biochemistry & Molecular Biology

Structural Studies of Amyloid Proteins at the Molecular Level

David S. Eisenberg et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 86 (2017)

Article Biochemistry & Molecular Biology

Solution Structures of Phenol-Soluble Modulins α1, α3, and β2, Virulence Factors from Staphylococcus aureus

Kaitlyn M. Towle et al.

BIOCHEMISTRY (2016)

Article Chemistry, Multidisciplinary

Designed, Helical Protein Nanotubes with Variable Diameters from a Single Building Block

Jeffrey D. Brodin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Chemistry, Physical

DNA nanotubes and helical nanotapes via self-assembly of ssDNA-amphiphiles

Timothy R. Pearce et al.

SOFT MATTER (2015)

Article Biochemistry & Molecular Biology

Structural Plasticity of Helical Nanotubes Based on Coiled-Coil Assemblies

E. H. Egelman et al.

STRUCTURE (2015)

Article Chemistry, Multidisciplinary

Correlation between Nanomechanics and Polymorphic Conformations in Amyloid Fibrils

Ivan Usov et al.

ACS NANO (2014)

Article Chemistry, Multidisciplinary

Peptide Nanotubes

Ian W. Hamley

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Biochemistry & Molecular Biology

Investigating the lytic activity and structural properties of Staphylococcus aureus phenol soluble modulin (PSM) peptide toxins

Maisem Laabei et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)

Review Microbiology

Phenol-soluble modulins - critical determinants of staphylococcal virulence

Gordon Y. C. Cheung et al.

FEMS MICROBIOLOGY REVIEWS (2014)

Article Chemistry, Multidisciplinary

Polymorphism Complexity and Handedness Inversion in Serum Albumin Amyloid Fibrils

Ivan Usov et al.

ACS NANO (2013)

Article Chemistry, Multidisciplinary

The Structure of Cross-beta Tapes and Tubes Formed by an Octapeptide, alpha S beta 1

Kyle L. Morris et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

Review Medicine, Research & Experimental

Staphylococcal Infections: Mechanisms of Biofilm Maturation and Detachment as Critical Determinants of Pathogenicity

Michael Otto

ANNUAL REVIEW OF MEDICINE, VOL 64 (2013)

Article Chemistry, Multidisciplinary

Tuning the Self-Assembly of Short Peptides via Sequence Variations

Yurong Zhao et al.

LANGMUIR (2013)

Review Microbiology

Phenol-soluble modulins and staphylococcal infection

Andreas Peschel et al.

NATURE REVIEWS MICROBIOLOGY (2013)

Review Biochemistry & Molecular Biology

Review self-assembly of amphipathic β-sheet peptides: Insights and applications

Charles J. Bowerman et al.

BIOPOLYMERS (2012)

Article Biochemistry & Molecular Biology

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

Sjors H. W. Scheres

JOURNAL OF STRUCTURAL BIOLOGY (2012)

Review Medicine, Research & Experimental

Antimicrobial Properties of Amyloid Peptides

Bruce L. Kagan et al.

MOLECULAR PHARMACEUTICS (2012)

Article Chemistry, Multidisciplinary

Direct Observation of Time-Resolved Polymorphic States in the Self-Assembly of End-Capped Heptapeptides

Jozef Adamcik et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

News Item Biophysics

Antimicrobial Amyloids?

Bruce L. Kagan

BIOPHYSICAL JOURNAL (2011)

Article Chemistry, Multidisciplinary

Unraveling the Mechanism of Nanotube Formation by Chiral Self-Assembly of Amphiphiles

Lior Ziserman et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Review Biochemistry & Molecular Biology

A Diversity of Assembly Mechanisms of a Generic Amyloid Fold

Timo Eichner et al.

MOLECULAR CELL (2011)

Article Physics, Multidisciplinary

Curvature Instability in a Chiral Amphiphile Self-Assembly

Lior Ziserman et al.

PHYSICAL REVIEW LETTERS (2011)

Article Multidisciplinary Sciences

Molecular basis for amyloid-β polymorphism

Jacques-Philippe Colletier et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Shape selection of twist-nematic-elastomer ribbons

Yoshiki Sawa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Biochemical Research Methods

Features and development of Coot

P. Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Biochemical Research Methods

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Article Microbiology

Human Formyl Peptide Receptor 2 Senses Highly Pathogenic Staphylococcus aureus

Dorothee Kretschmer et al.

CELL HOST & MICROBE (2010)

Article Medicine, General & Internal

Community-associated meticillin-resistant Staphylococcus aureus

Frank R. DeLeo et al.

LANCET (2010)

Article Biochemistry & Molecular Biology

Structural polymorphism in F-actin

Vitold E. Galkin et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)

Review Microbiology

Waves of resistance: Staphylococcus aureus in the antibiotic era

Henry F. Chambers et al.

NATURE REVIEWS MICROBIOLOGY (2009)

Article Biochemistry & Molecular Biology

Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA

Rong Wang et al.

NATURE MEDICINE (2007)

Review Biochemistry & Molecular Biology

Inference of macromolecular assemblies from crystalline state

Evgeny Krissinel et al.

JOURNAL OF MOLECULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

EMAN2: An extensible image processing suite for electron microscopy

Guang Tang et al.

JOURNAL OF STRUCTURAL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

The iterative helical real space reconstruction method: Surmounting the problems posed by real polymers

Edward H. Egelman

JOURNAL OF STRUCTURAL BIOLOGY (2007)

Article Physics, Multidisciplinary

Helicoid to spiral ribbon transition

R Ghafouri et al.

PHYSICAL REVIEW LETTERS (2005)

Article Mathematics, Applied

Visualizing chiral self-assembly

RLB Selinger et al.

CHAOS (2004)

Article Physics, Multidisciplinary

Shape selection in chiral self-assembly

RLB Selinger et al.

PHYSICAL REVIEW LETTERS (2004)

Article Chemistry, Multidisciplinary

UCSF chimera - A visualization system for exploratory research and analysis

EF Pettersen et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Cross-beta order and diversity in nanocrystals of an amyloid-forming peptide

R Diaz-Avalos et al.

JOURNAL OF MOLECULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Accurate determination of local defocus and specimen tilt in electron microscopy

JA Mindell et al.

JOURNAL OF STRUCTURAL BIOLOGY (2003)

Article Chemistry, Multidisciplinary

Exploiting amyloid fibril lamination for nanotube self-assembly

K Lu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)

Article Chemistry, Multidisciplinary

Responsive hydrogels from the intramolecular folding and self-assembly of a designed peptide

JP Schneider et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

Article Multidisciplinary Sciences

The protofilament structure of insulin amyloid fibrils

JL Jimenez et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Chemistry, Multidisciplinary

Left-handed helical ribbon intermediates in the self-assembly of a β-sheet peptide

DM Marini et al.

NANO LETTERS (2002)