Journal
POLYCYCLIC AROMATIC COMPOUNDS
Volume 43, Issue 3, Pages 2672-2679Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10406638.2022.2052119
Keywords
1-Aryl-1-phenyl-1H-pyrazole-4-carbaldehyde; thiosemicarbazide; orthophosphoric acid; multicomponent reaction
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This study reported a one-pot multicomponent synthesis method for the synthesis of novel compounds, which is environmentally friendly, rapid, and yields products with good to excellent yield.
Present investigation reported one-pot multicomponent synthesis of novel series of 8-benzyloxy-5-{2-[N '-(1,3-diphenyl-1H-pyrazol-4-ylmethylene)-hydrazino]-thiazol-4-yl}-3,4-dihydro-1H-quinolin-2-one derivatives. The titled compounds were synthesized by using one-pot condensation of substituted 3-aryl-1-phenyl-1H-pyrazole-4-carbaldehyde, thiosemicarbazide, and 8-benzyloxy-5-(2-bromo-acetyl)-1H-quinolin-2-one. Main features of present protocol are environmentally benign, rapid and good to excellent yield of the products (93-99%).
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