4.3 Article

Ganoellipsic acids A-C, lanostane triterpenoids from artificially cultivated fruiting bodies of Ganoderma ellipsoideum

Journal

PHYTOCHEMISTRY LETTERS
Volume 49, Issue -, Pages 27-31

Publisher

ELSEVIER
DOI: 10.1016/j.phytol.2022.03.001

Keywords

Ganoderma ellipsoideum; Ganodermataceae; Lanostane triterpenes; PGME method

Funding

  1. Thailand Research Fund, Thailand [DBG6280008]
  2. National Natural Science Foundation of China, China [21961142008]

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Three new lanostane triterpenoids, named ganoellipsic acids A-C (1-3), along with seven known Ganoderma lanostanoids (4-10), were isolated from artificially cultivated fruiting bodies of Ganoderma ellipsoideum, strain BCC 16634. The structures of these compounds were determined by NMR spectroscopy and mass spectrometry. The absolute configuration of compound 1 at C-25 was found to be 25S using the phenylglycine methyl ester (PGME) method.
Three undescribed lanostane triterpenoids, ganoellipsic acids A-C (1-3), together with seven known Ganoderma lanostanoids (4-10), were isolated from artificially cultivated fruiting bodies of Ganoderma ellipsoideum, strain BCC 16634. The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data. The C-25 absolute configuration of 1 was determined to be 25S using the phenylglycine methyl ester (PGME) method.

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