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Abolfazl Akbarzadeh et al.
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Chun Shi et al.
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Fang Fang et al.
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Kang-Woo Lee et al.
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Bo Jiang et al.
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Y. Zong et al.
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X. Liu et al.
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Ryo Hashimoto et al.
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Wen-Che Tsai et al.
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Jing Zhang et al.
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Samuel H. H. Chan et al.
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Lorenzo Galluzzi et al.
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Jae-Hyeok Heo et al.
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Eric Y. H. Chen et al.
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Ginsenosides and Their CNS Targets
Khaled Radad et al.
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Liang Li et al.
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Anil Mahapatro et al.
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Chang-Su Park et al.
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Yan-Qing Shi et al.
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Xiao-Qing Gao et al.
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Distinct 3′UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF)
Anthony G. Lau et al.
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Andrew Scholey et al.
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Kar Leung et al.
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Young-Jin Ryu et al.
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Haifeng Zhao et al.
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Min Han et al.
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Haifeng Zhao et al.
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Ming-Chin Lu et al.
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Bayani Uttara et al.
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X. Liu et al.
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Rajesh Singh et al.
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Yi Gu et al.
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Naoto Matsuda et al.
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Suzanne Timmons et al.
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Volkmar Lessmann et al.
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Cristina M. Alberini
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W. Wei-Lynn Wong et al.
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J. Jankovic
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A. J. Hulbert et al.
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Hao-Ji Wei et al.
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Fanzhu Li et al.
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K. W. Leung et al.
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Jian-Fei Xue et al.
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LB Li et al.
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J. M. Koziara et al.
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DA Greenberg et al.
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E Mariani et al.
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Y Gao et al.
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S Goodenough et al.
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J Van Kampen et al.
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ACH Chen et al.
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VLR Rao et al.
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