4.4 Article

Pharmacist-administered audiology screening for pediatric cystic fibrosis patients exposed to high-dose aminoglycosides: A pilot study

Journal

PEDIATRIC PULMONOLOGY
Volume 57, Issue 7, Pages 1814-1817

Publisher

WILEY
DOI: 10.1002/ppul.25946

Keywords

aminoglycosides; audiology; cystic fibrosis; ototoxicity

Funding

  1. Eshelman Institute for Innovation, University of North Carolina at Chapel Hill

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This pilot study successfully introduced a standardized tablet-based ototoxicity screening for pediatric CF patients. More research is needed to evaluate its impact and identify potential barriers. This method provides an accessible alternative to audiology testing and is crucial for early detection of medication-related toxicities in CF patients.
This pilot study successfully implemented a standardized protocol for tablet-based ototoxicity screening in pediatric cystic fibrosis (CF) patients exposed to aminoglycosides. Further studies are needed to assess the impact of implementation in a larger number of patients, as well as to determine barriers that may exist at centers with variation in available resources. This method of ototoxicity screening represents an accessible alternative to traditional audiology testing, and given the continued improvements in expected life span for people with CF, it is imperative that patients have regular access to this type of screening to allow for early identification of medication-related toxicities.

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