Iridium(III)-Catalyzed Regioselective B(4)-H Allenylation of o-Carboranes by Ball Milling

We disclose an iridium(III)-catalyzed regioselective B(4)-H allenylation of o-carboranes from o-carborane acids and propargyl carbonates under ball-milling conditions. This study sheds light on a novel method to accomplish regioselective B(4)- allenylation of o-carborane that cannot be realized through conventional solution-based reactions. Control experiments, including solution, neat, microwave, and high-temperature reactions, reveal that the B(4)-H allenylation of o-carborane is unique for ballmilling conditions.

Automated summary

This study presents a novel method for achieving regioselective B(4)-H allenylation of o-carboranes under ball-milling conditions, which cannot be achieved through conventional solution-based reactions.