Journal
ORGANIC LETTERS
Volume 24, Issue 13, Pages 2567-2572Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.2c00808
Keywords
-
Categories
Ask authors/readers for more resources
This study reports a kinetically controllable strategy for the construction of challenging nine-membered carbocycles. The Pd-catalyzed decarboxylative procedure uses vinyl methylene cyclic carbonates as the C5-dipole and allylidenemalononitriles as C4-building blocks. The protocol features user-friendly operations with controllable regioselectivity and produces CO2 as the sole byproduct. The formation of synthetically valuable and thermodynamically favored seven-membered carbocycles was also investigated.
A kinetically controllable strategy toward the construction of otherwise challenging nine-membered carbocycles is reported. This Pd-catalyzed decarboxylative procedure utilizes vinyl methylene cyclic carbonates as the C5-dipole and allylidenemalononitriles as C4-building blocks. The protocol features user-friendly operations with controllable regioselectivity and generates CO2 as the sole byproduct. The formation of synthetically valuable and thermodynamically favored seven-membered carbocycles was also investigated.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available