4.6 Article

Non-invasive chemically selective energy delivery and focusing inside a scattering medium guided by Raman scattering

Journal

OPTICS LETTERS
Volume 47, Issue 9, Pages 2145-2148

Publisher

Optica Publishing Group
DOI: 10.1364/OL.456411

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Funding

  1. Xi'an Technological University
  2. HORIZON EUROPE Marie Sklodowska-Curie Actions [888707]
  3. H2020 Future and Emerging Technologies [863203]
  4. European Research Council [724473]
  5. Agence Nationale de la Recherche via LabEX ENS-ICFP [ANR-10-IDEX-0001-02 PSL*, ANR-10-LABX-0010]
  6. European Research Council (ERC) [724473] Funding Source: European Research Council (ERC)
  7. Marie Curie Actions (MSCA) [888707] Funding Source: Marie Curie Actions (MSCA)
  8. Agence Nationale de la Recherche (ANR) [ANR-10-LABX-0010] Funding Source: Agence Nationale de la Recherche (ANR)

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In this study, we demonstrate chemically selective energy deposition behind a scattering medium by combining prior information on the chemical's spectrum with the measurement of a spectrally resolved Raman speckle as a feedback mechanism for wavefront shaping. We achieve unprecedented sixfold signal enhancement in an epi-geometry, realizing targeted energy deposition and focusing on individual Raman active particles.
Raman scattering is a chemically selective probing mechanism with diverse applications in industry and clinical settings. Yet, most samples are optically opaque limiting the applicability of Raman probing at depth. Here, we demonstrate chemically selective energy deposition behind a scattering medium by combining prior information on the chemical's spectrum with the measurement of a spectrally resolved Raman speckle as a feedback mechanism for wavefront shaping. We demonstrate unprecedented sixfold signal enhancement in an epi-geometry, realizing targeted energy deposition and focusing on individual Raman active particles. (C) 2022 Optica Publishing Group

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