Large-field structured illumination microscopy based on 2D grating and a spatial light modulator

Article Chemistry, Multidisciplinary

High-Refractive-Index Chip with Periodically Fine-Tuning Gratings for Tunable Virtual-Wavevector Spatial Frequency Shift Universal Super-Resolution Imaging

Mingwei Tang et al.

Summary: This study introduces a universal super-resolution imaging method based on the tunable virtual-wavevector spatial frequency shift (TVSFS) principle, which can achieve labeled and label-free super-resolution imaging on a single scalable photonic chip. With this method, imaging resolution can be improved more than threefold over the diffraction limit of a linear optical system.

ADVANCED SCIENCE (2022)

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Article Optics

High-throughput optical sectioning via line-scanning imaging with digital structured modulation

Qiuyuan Zhong et al.

Summary: This study introduces a new method for optical sectioning imaging that achieves higher image quality and throughput compared to traditional methods. By imaging large biological tissue samples, it opens up new possibilities for the development of high-throughput, high-resolution optical imaging methods.

OPTICS LETTERS (2021)

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Article Biochemical Research Methods

Multicolor structured illumination microscopy and quantitative control of polychromatic light with a digital micromirror device

Peter T. Brown et al.

Summary: Linear structured illumination microscopy (SIM) is a super-resolution technique that works well with fluorescent samples. While multicolor SIM usually uses LCoS spatial light modulators (SLM's), digital micromirror devices (DMD's) are becoming a promising alternative due to their cost-effectiveness and speed. However, current coherent DMD SIM implementations are limited to a single wavelength of light, lacking efficient approaches for handling polychromatic light.

BIOMEDICAL OPTICS EXPRESS (2021)

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Article Optics

Structured illumination microscopy with partially coherent illumination for phase and fluorescent imaging

Kai Wen et al.

Summary: This study introduces a partially coherent illumination-based SIM apparatus for dual-modality microscopic imaging, capable of obtaining phase and fluorescent images of the same sample. The system demonstrates superiority in phase and fluorescent imaging, with potential applications in various fields.

OPTICS EXPRESS (2021)

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Article Optics