4.7 Article

Phase I Trial of Regorafenib, Hydroxychloroquine, and Entinostat in Metastatic Colorectal Cancer

Related references

Note: Only part of the references are listed.
Article Oncology

Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti-PD-(L)1 Therapy

Matthew D. Hellmann et al.

Summary: In patients with NSCLC who had previous experience with PD-(L)1, the combination of entinostat and pembrolizumab did not meet the primary response rate endpoint but provided a clinically meaningful benefit, with 9% of patients showing objective response. No new toxicities, including immune-related adverse events, were observed.

CLINICAL CANCER RESEARCH (2021)

Article Oncology

E2112: Randomized Phase III Trial of Endocrine Therapy Plus Entinostat or Placebo in Hormone Receptor-Positive Advanced Breast Cancer. A Trial of the ECOG-ACRIN Cancer Research Group

Roisin M. Connolly et al.

Summary: The combination of entinostat and exemestane did not improve survival in patients with AI-resistant advanced HR-positive, HER2-negative breast cancer. E2112 phase III trial: no benefit seen in adding HDAC inhibitor entinostat to exemestane in advanced breast cancer.

JOURNAL OF CLINICAL ONCOLOGY (2021)

Article Multidisciplinary Sciences

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

Keisuke Yamamoto et al.

NATURE (2020)

Review Oncology

Antiangiogenic tyrosine kinase inhibitors in colorectal cancer: is there a path to making them more effective?

Thomas B. Karasic et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2017)

Article Oncology

Autophagy Inhibition Sensitizes Colon Cancer Cells to Antiangiogenic and Cytotoxic Therapy

Muthu Selvakumaran et al.

CLINICAL CANCER RESEARCH (2013)

Article Medicine, Research & Experimental

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

Ravi K. Amaravadi et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Medicine, General & Internal

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

H Hurwitz et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)