Journal
OCULAR IMMUNOLOGY AND INFLAMMATION
Volume 31, Issue 3, Pages 477-482Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/09273948.2022.2032193
Keywords
Biologic response modifier; birdshot chorioretinopathy; BSCR; corticosteroid; electroretinography; fluorescein angiography; immunomodulatory therapy; indocyanine green angiography; retinal vasculitis; visual field; short wavelength automated perimetry
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This study found that small vessel leakage in the macular area and/or optic nerve head leakage may be risk factors for resistant birdshot chorioretinopathy.
Purpose To search findings that can explain the heterogeneity between Resistant and Responsive patients with birdshot chorioretinopathy. Patients and Methods This was a retrospective observational case series on Responsive versus Resistant birdshot chorioretinopathy Results One-hundred-eighty and Ninety-nine patients were included in the Responsive and Resistant groups respectively. Multivariate analysis of paraclinical variables at the first visit demonstrated that mean deviation (p = .04), pattern standard deviation (p < .001), optic nerve head leakage (p = .012), large vessel leakage and staining (p = .01), and macular small vessel leakage (p = .03) were statistically significantly different between the two groups; however, at the visit preceding successful therapy, only macular small vessel leakage (p = .01) was statistically significantly different between the two groups Conclusion .Small vessel leakage in the macular area and/or optic nerve head leakage at the earliest visit might be risk factors for resistant birdshot chorioretinopathy.
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