4.8 Editorial Material

Baricitinib in Alopecia Areata

Journal

NEW ENGLAND JOURNAL OF MEDICINE
Volume 386, Issue 18, Pages 1751-1752

Publisher

MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMe2203440

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For many individuals, alopecia areata is a temporary issue with hair loss patches recovering spontaneously within a few months. However, for a significant portion of patients, this condition can persist long-term and progress to complete baldness, with limited chances of recovery. Severe cases of alopecia often do not respond to medical treatments, leaving patients to struggle with the challenges it presents.
For many people, alopecia areata is a transient problem, in which small patches of hair loss recover spontaneously within a few months. But for others, the reality is rather different. An Italian study showed that one third of patients with scalp hair loss of 25 to 50% still had active patchy disease at long-term follow-up, with a further third having progression to alopecia totalis or alopecia universalis, terms that vividly capture the extreme extent of disease and from which recovery is rare.(1) For many patients with severe disease, medical treatments do not work, and they face difficulty in coping with . . .

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