Related references
Note: Only part of the references are listed.Molecular characterization of selectively vulnerable neurons in Alzheimer's disease
Kun Leng et al.
NATURE NEUROSCIENCE (2021)
Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease
Emma Gerrits et al.
ACTA NEUROPATHOLOGICA (2021)
Neurotoxic reactive astrocytes induce cell death via saturated lipids
Kevin A. Guttenplan et al.
NATURE (2021)
Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex
Kristen R. Maynard et al.
NATURE NEUROSCIENCE (2021)
Integrated analysis of multimodal single-cell data
Yuhan Hao et al.
CELL (2021)
Spatial transcriptomics at subspot resolution with BayesSpace
Edward Zhao et al.
NATURE BIOTECHNOLOGY (2021)
Neuroinflammatory astrocyte subtypes in the mouse brain
Philip Hasel et al.
NATURE NEUROSCIENCE (2021)
2021 Alzheimer's disease facts and figures
[Anonymous]
ALZHEIMERS & DEMENTIA (2021)
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease
Yingyue Zhou et al.
NATURE MEDICINE (2020)
Orchestrating single-cell analysis with Bioconductor
Robert A. Amezquita et al.
NATURE METHODS (2020)
Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration
Heather L. Smith et al.
NEURON (2020)
Depletion of LncRNA NEAT1 Rescues Mitochondrial Dysfunction Through NEDD4L-Dependent PINK1 Degradation in Animal Models of Alzheimer's Disease
Zhonghua Huang et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2020)
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study
Eric M. Reiman et al.
NATURE COMMUNICATIONS (2020)
Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map
Omer Ali Bayraktar et al.
NATURE NEUROSCIENCE (2020)
CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes
Lilianne Barbar et al.
NEURON (2020)
Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model
Kevin A. Guttenplan et al.
NATURE COMMUNICATIONS (2020)
Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer's disease
Shun-Fat Lau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Association of APOE e2 genotype with Alzheimer's and non-Alzheimer's neurodegenerative pathologies
Terry E. Goldberg et al.
NATURE COMMUNICATIONS (2020)
Dual-Specificity Phosphatases in Neuroblastoma Cell Growth and Differentiation
Caroline E. Nunes-Xavier et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Single-cell transcriptomic analysis of Alzheimer's disease
Hansruedi Mathys et al.
NATURE (2019)
CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes
Penelope Dimas et al.
ELIFE (2019)
Comprehensive Integration of Single-Cell Data
Tim Stuart et al.
CELL (2019)
被撤回的出版物: ADAMTS13 maintains cerebrovascular integrity to ameliorate Alzheimer-like pathology (Retracted article. See vol. 21, 2023)
Yongliang Cao et al.
PLOS BIOLOGY (2019)
Conserved cell types with divergent features in human versus mouse cortex
Rebecca D. Hodge et al.
NATURE (2019)
A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain
Jorge L. Del-Aguila et al.
ALZHEIMERS RESEARCH & THERAPY (2019)
Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy
Tiffany Wu et al.
CELL REPORTS (2019)
Blood transcriptomic biomarker as a surrogate of ischemic brain gene expression
LeeAnn Ramsay et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2019)
Fast, sensitive and accurate integration of single-cell data with Harmony
Ilya Korsunsky et al.
NATURE METHODS (2019)
A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation
Alexandra Grubman et al.
NATURE NEUROSCIENCE (2019)
Brain cell type-specific enhancer-promoter interactome maps and disease-risk association
Alexi Nott et al.
SCIENCE (2019)
Astrocyte molecular signatures in Huntington's disease
Blanca Diaz-Castro et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Don't forget astrocytes when targeting Alzheimer's disease
Jessica S. Sadick et al.
BRITISH JOURNAL OF PHARMACOLOGY (2019)
Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression
Christoph Hafemeister et al.
GENOME BIOLOGY (2019)
Novel Phosphodiesterase Inhibitors for Cognitive Improvement in Alzheimer's Disease
Yinuo Wu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Normal aging induces A1-like astrocyte reactivity
Laura E. Clarke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
A general and flexible method for signal extraction from single-cell RNA-seq data
Davide Risso et al.
NATURE COMMUNICATIONS (2018)
The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain
Matthew M. Boisvert et al.
CELL REPORTS (2018)
SALM/Lrfn Family Synaptic Adhesion Molecules
Eunkyung Lie et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
The Emerging Role of Mechanics in Synapse Formation and Plasticity
Devrim Kilinc
FRONTIERS IN CELLULAR NEUROSCIENCE (2018)
Investigational phosphodiesterase inhibitors in phase I and phase II clinical trials for Alzheimer's disease
Jos Prickaerts et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2017)
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
Yang Shi et al.
NATURE (2017)
Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis
Jeff A. Stogsdill et al.
NATURE (2017)
Neurotoxic reactive astrocytes are induced by activated microglia
Shane A. Liddelow et al.
NATURE (2017)
Heparan sulfate proteoglycans and heparanases in Alzheimer's disease: current outlook and potential therapeutic targets
Laura Lorente-Gea et al.
NEURAL REGENERATION RESEARCH (2017)
Involvement of Astrocytes in Alzheimer's Disease from a Neuroinflammatory and Oxidative Stress Perspective
Rodrigo E. Gonzalez-Reyes et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
QuPath: Open source software for digital pathology image analysis
Peter Bankhead et al.
SCIENTIFIC REPORTS (2017)
Regulator of Cell Cycle (RGCC) Expression During the Progression of Alzheimer's Disease
Scott E. Counts et al.
CELL TRANSPLANTATION (2017)
White Matter Hyperintensities Are a Core Feature of Alzheimer's Disease: Evidence from the Dominantly Inherited Alzheimer Network
Seonjoo Lee et al.
ANNALS OF NEUROLOGY (2016)
Role of P-glycoprotein in mediating rivastigmine effect on amyloid-β brain load and related pathology in Alzheimer's disease mouse model
Loqman A. Mohamed et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)
Complex heatmaps reveal patterns and correlations in multidimensional genomic data
Zuguang Gu et al.
BIOINFORMATICS (2016)
The Cellular Phase of Alzheimer's Disease
Bart De Strooper et al.
CELL (2016)
The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting
Christopher S. von Bartheld et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2016)
Selective vulnerability in neurodegeneration: insights from clinical variants of Alzheimer's disease
Niklas Mattsson et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2016)
Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease
Hong Lian et al.
JOURNAL OF NEUROSCIENCE (2016)
A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism
Li Zhong et al.
MOLECULAR NEURODEGENERATION (2016)
Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism
Aiman S. Saab et al.
NEURON (2016)
Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
Ye Zhang et al.
NEURON (2016)
Complement and microglia mediate early synapse loss in Alzheimer mouse models
Soyon Hong et al.
SCIENCE (2016)
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
Itay Tirosh et al.
SCIENCE (2016)
Galantamine attenuates amyloid-β deposition and astrocyte activation in APP/PS1 transgenic mice
Zhaoxuan Wu et al.
EXPERIMENTAL GERONTOLOGY (2015)
The promise of stem cells in the therapy of Alzheimer's disease
Chunmei Yue et al.
TRANSLATIONAL NEURODEGENERATION (2015)
Targeted quantitative analysis of synaptic proteins in Alzheimer's disease brain
Rachel Yoon Kyung Chang et al.
NEUROCHEMISTRY INTERNATIONAL (2014)
Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination
Yasir A. Syed et al.
EMBO MOLECULAR MEDICINE (2013)
White matter abnormalities associated with Alzheimer's disease and mild cognitive impairment: a critical review of MRI studies
Marcia Radanovic et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2013)
APOE-ε2 and APOE-ε4 Correlate With Increased Amyloid Accumulation in Cerebral Vasculature
Peter T. Nelson et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2013)
MAP Kinase Phosphatase 1 (MKP-1/DUSP1) Is Neuroprotective in Huntington's Disease via Additive Effects of JNK and p38 Inhibition
David M. Taylor et al.
JOURNAL OF NEUROSCIENCE (2013)
Mitogen-Activated Protein Kinase Phosphatase (MKP)-1 as a Neuroprotective Agent: Promotion of the Morphological Development of Midbrain Dopaminergic Neurons
Louise M. Collins et al.
NEUROMOLECULAR MEDICINE (2013)
Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease
Azeb Tadesse Argaw et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Genomic Analysis of Reactive Astrogliosis
Jennifer L. Zamanian et al.
JOURNAL OF NEUROSCIENCE (2012)
Evidence for Astrocytosis in Prodromal Alzheimer Disease Provided by 11C-Deuterium-L-Deprenyl: A Multitracer PET Paradigm Combining 11C-Pittsburgh Compound B and 18F-FDG
Stephen F. Carter et al.
JOURNAL OF NUCLEAR MEDICINE (2012)
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity
Ursula Fuenfschilling et al.
NATURE (2012)
Fiji: an open-source platform for biological-image analysis
Johannes Schindelin et al.
NATURE METHODS (2012)
Cerebral amyloid angiopathy in the elderly
Anand Viswanathan et al.
ANNALS OF NEUROLOGY (2011)
Cholesterol Level and Statin Use in Alzheimer Disease I. Review of Epidemiological and Preclinical Studies
Nina E. Shepardson et al.
ARCHIVES OF NEUROLOGY (2011)
N-cadherin Regulates p38 MAPK Signaling via Association with JNK-associated Leucine Zipper Protein IMPLICATIONS FOR NEURODEGENERATION IN ALZHEIMER DISEASE
Koichi Ando et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study
Melissa E. Murray et al.
LANCET NEUROLOGY (2011)
Cholesterol: A Novel Regulatory Role in Myelin Formation
Gesine Saher et al.
NEUROSCIENTIST (2011)
High Degree of Heterogeneity in Alzheimer's Disease Progression Patterns
Natalia L. Komarova et al.
PLOS COMPUTATIONAL BIOLOGY (2011)
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
Mark D. Robinson et al.
BIOINFORMATICS (2010)
DISC1 regulates N-cadherin and β1-integrin expression in neurons
T Hattori et al.
MOLECULAR PSYCHIATRY (2010)
Polyamine pathway contributes to the pathogenesis of Parkinson disease
Nicole M. Lewandowski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Biochemical and physiological function of stearoyl-CoA desaturase
Chad M. Paton et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Proteomics-Determined Differences in the Concanavalin-A-Fractionated Proteome of Hippocampus and Inferior Parietal Lobule in Subjects with Alzheimer's Disease and Mild Cognitive Impairment: Implications for Progression of AD
Joshua B. Owen et al.
JOURNAL OF PROTEOME RESEARCH (2009)
Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt
Steffen Durinck et al.
NATURE PROTOCOLS (2009)
Mitogen-activated protein (MAP) Kinase/MAP kinase phosphatase regulation: Roles in cell growth, death, and cancer
Tarek Boutros et al.
PHARMACOLOGICAL REVIEWS (2008)
Expression changes in mouse brains following nicotine-induced seizures: the modulation of transcription factor networks
Merav Kedmi et al.
PHYSIOLOGICAL GENOMICS (2007)
Phosphodiesterase inhibitors
V Boswell-Smith et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment
HM Schipper et al.
NEUROBIOLOGY OF AGING (2006)
High cholesterol level is essential for myelin membrane growth
G Saher et al.
NATURE NEUROSCIENCE (2005)
Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response
HY Jiang et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
New roles for astrocytes: Redefining the functional architecture of the brain
M Nedergaard et al.
TRENDS IN NEUROSCIENCES (2003)
Alzheimer's disease is associated with a selective increase in α7 nicotinic acetylcholine receptor immunoreactivity in astrocytes
T Teaktong et al.
GLIA (2003)
Cholesterol, a modulator of membrane-associated Aβ-fibrillogenesis and neurotoxicity
CM Yip et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Cerebral microvascular pathology in aging and Alzheimer's disease
E Farkas et al.
PROGRESS IN NEUROBIOLOGY (2001)
N-cadherin is involved in axon-oligodendrocyte contact and myelination
O Schnädelbach et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2001)
VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain
ZG Zhang et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
LM Refolo et al.
NEUROBIOLOGY OF DISEASE (2000)