Ethical Guidance for Neuroprognostication in Disorders of Consciousness

Article Clinical Neurology

Ethics and the 2018 Practice Guideline on Disorders of Consciousness A Framework for Responsible Implementation

Andrew Peterson et al.

Summary: The 2018 practice guideline on disorders of consciousness is a significant milestone for the care of patients with severe brain injury. However, implementing the guideline in clinical practice will raise ethical challenges, such as assessing the benefits, harms, feasibility, and cost of recommended interventions. To aid clinicians in interpreting the recommendations, it is crucial for professional societies to develop an ethical framework.

NEUROLOGY (2022)

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Editorial Material Clinical Neurology

Holding Out Hope After Traumatic Brain Injury

Jennifer A. Kim et al.

JAMA NEUROLOGY (2021)

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Article Clinical Neurology

Recovery of Consciousness and Functional Outcome in Moderate and Severe Traumatic Brain Injury

Robert G. Kowalski et al.

Summary: This study found that most patients with TBI initially experienced DOC, and it persisted in some patients after rehabilitation, but the majority of those with persisting DOC recovered consciousness during rehabilitation.

JAMA NEUROLOGY (2021)

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Article Clinical Neurology

Functional Outcomes Over the First Year After Moderate to Severe Traumatic Brain Injury in the Prospective, Longitudinal TRACK-TBI Study

Michael A. McCrea et al.

Summary: This study prospectively assessed outcomes in major areas of life function at 2 weeks and 3, 6, and 12 months after moderate to severe traumatic brain injury (msTBI). The results showed that patients with msTBI frequently demonstrated major functional gains and recovery of independence between 2 weeks and 12 months postinjury, cautioning against early, definitive prognostic statements suggesting poor outcomes.

JAMA NEUROLOGY (2021)

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Article Clinical Neurology

Practice guideline update recommendations summary: Disorders of consciousness Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology; the American Congress of Rehabilitation Medicine; and the National Institute on Disability, Independent Living, and Rehabilitation Research

Joseph T. Giacino et al.

NEUROLOGY (2018)

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Article Critical Care Medicine

Self-Fulfilling Prophecies Through Withdrawal of Care: Do They Exist in Traumatic Brain Injury, Too?

Saef Izzy et al.

NEUROCRITICAL CARE (2013)

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Article Medicine, General & Internal

Mortality associated with withdrawal of life-sustaining therapy for patients with severe traumatic brain injury: a Canadian multicentre cohort study

Alexis F. Turgeon et al.

CANADIAN MEDICAL ASSOCIATION JOURNAL (2011)

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Ethical Guidance for Neuroprognostication in Disorders of Consciousness

Related references

Ethics and the 2018 Practice Guideline on Disorders of Consciousness A Framework for Responsible Implementation

Holding Out Hope After Traumatic Brain Injury

Recovery of Consciousness and Functional Outcome in Moderate and Severe Traumatic Brain Injury

Functional Outcomes Over the First Year After Moderate to Severe Traumatic Brain Injury in the Prospective, Longitudinal TRACK-TBI Study

Self-Fulfilling Prophecies Through Withdrawal of Care: Do They Exist in Traumatic Brain Injury, Too?

Mortality associated with withdrawal of life-sustaining therapy for patients with severe traumatic brain injury: a Canadian multicentre cohort study

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