The cost of resistance

This study shows that although colistin resistance in Klebsiella pneumoniae is associated with a fitness defect in gut colonization, it increases bacterial survival outside the host, thus enabling efficient host-to-host transmission.

Automated summary

This study demonstrates that colistin resistance in Klebsiella pneumoniae leads to a fitness defect in gut colonization, while enhancing bacterial survival outside the host, thus facilitating efficient host-to-host transmission.