Journal
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
Volume 19, Issue 6, Pages 347-348Publisher
NATURE PORTFOLIO
DOI: 10.1038/s41575-022-00609-7
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Funding
- National Institute of Dental and Craniofacial Research of the NIH [R01 DE027850]
- National Cancer Institute (NCI) [R00 CA229984-03]
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This article discusses the importance of intratumoural microbiome research and its potential applications in gastrointestinal cancers.
The burgeoning field of intratumoural microbiome research has been driven by advances in next-generation sequencing technologies, with compelling evidence on the role of the microbiota in cancer initiation, progression and patient response to treatment. Here, we discuss new concepts of the tumour-associated microbiota and what is needed to advance the translational impact of these findings in gastrointestinal cancers.
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