4.8 Article

Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

An approach for normalization and quality control for NanoString RNA expression data

Arjun Bhattacharya et al.

Summary: The NanoString RNA counting assay is sensitive and reproducible for formalin-fixed paraffin embedded samples. A comprehensive normalization procedure developed here eliminates technical variation more reliably without diminishing biological variation, emphasizing the importance of systematic quality control, normalization, and visualization of NanoString nCounter data.

BRIEFINGS IN BIOINFORMATICS (2021)

Article Biochemistry & Molecular Biology

Emerging roles for IL-6 family cytokines as positive and negative regulators of ectopic lymphoid structures

David G. Hill et al.

Summary: IL-6 family cytokines play important roles in regulating immune homeostasis, host defence, hematopoiesis, and development, while dysregulation of these activities may lead to autoimmunity, chronic inflammation, and cancer. Ectopic lymphoid structures (ELS) can support local antigen-specific responses and are associated with disease progression in autoimmune conditions and favorable prognosis in cancer.

CYTOKINE (2021)

Review Immunology

The growing role of precision medicine for the treatment of autoimmune diseases; results of a systematic review of literature and Experts' Consensus

Roberto Giacomelli et al.

Summary: Autoimmune diseases share common clinical features but have different pathogenic mechanisms and targeted organs. Applying precision medicine principles may improve treatment success by tailoring therapy to individual characteristics and reducing adverse events.

AUTOIMMUNITY REVIEWS (2021)

Review Immunology

Fibroblast pathology in inflammatory joint disease

Lucy-Jayne Marsh et al.

Summary: Rheumatoid arthritis is an immune-mediated inflammatory disease where fibroblasts play a significant role, both in maintaining joint homeostasis and promoting disease progression during inflammation. Recent studies have revealed the heterogeneity of fibroblasts, challenging the previous notion of their homogeneity and providing new insights into their role in inflammatory joint pathology.

IMMUNOLOGICAL REVIEWS (2021)

Article Multidisciplinary Sciences

B cells and tertiary lymphoid structures promote immunotherapy response

Beth A. Helmink et al.

NATURE (2020)

Article Multidisciplinary Sciences

M3C: Monte Carlo reference-based consensus clustering

Christopher R. John et al.

SCIENTIFIC REPORTS (2020)

Article Multidisciplinary Sciences

Notch signalling drives synovial fibroblast identity and arthritis pathology

Kevin Wei et al.

NATURE (2020)

Article Rheumatology

Translating IL-6 biology into effective treatments

Ernest H. Choy et al.

NATURE REVIEWS RHEUMATOLOGY (2020)

Review Rheumatology

PAD enzymes in rheumatoid arthritis: pathogenic effectors and autoimmune targets

Ashley M. Curran et al.

NATURE REVIEWS RHEUMATOLOGY (2020)

Article Rheumatology

Transforming clinical trials in rheumatology: towards patient-centric precision medicine

Costantino Pitzalis et al.

NATURE REVIEWS RHEUMATOLOGY (2020)

Article Health Care Sciences & Services

Sample size requirements for learning to classify with high-dimensional biomarker panels

Paul McKeigue

STATISTICAL METHODS IN MEDICAL RESEARCH (2019)

Article Multidisciplinary Sciences

Distinct fibroblast subsets drive inflammation and damage in arthritis

Adam P. Croft et al.

NATURE (2019)

Article Multidisciplinary Sciences

Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts

Nicola Ferrari et al.

NATURE COMMUNICATIONS (2019)

Article Rheumatology

Defining refractory rheumatoid arthritis

Maya H. Buch

ANNALS OF THE RHEUMATIC DISEASES (2018)

Article Multidisciplinary Sciences

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

Fumitaka Mizoguchi et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation

William Stephenson et al.

NATURE COMMUNICATIONS (2018)

Article Medicine, General & Internal

Rheumatoid arthritis

Josef S. Smolen et al.

NATURE REVIEWS DISEASE PRIMERS (2018)

Article Biochemical Research Methods

Salmon provides fast and bias-aware quantification of transcript expression

Rob Patro et al.

NATURE METHODS (2017)

Article Medicine, General & Internal

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer

H. Borghaei et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Biotechnology & Applied Microbiology

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

Charity W. Law et al.

GENOME BIOLOGY (2014)

Article Biotechnology & Applied Microbiology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love et al.

GENOME BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Prolectin, a Glycan-binding Receptor on Dividing B Cells in Germinal Centers

Sarah A. Graham et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Rheumatology

Immunohistochemical analysis as a means to predict responsiveness to rituximab treatment

Y. K. Onno Teng et al.

ARTHRITIS AND RHEUMATISM (2007)