Related references
Note: Only part of the references are listed.Understanding insulin and its receptor from their three-dimensional structures
Michael C. Lawrence
MOLECULAR METABOLISM (2021)
Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain
Theresia Gutmann et al.
JOURNAL OF CELL BIOLOGY (2020)
A structurally minimized yet fully active insulin based on cone-snail venom insulin principles
Xiaochun Xiong et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)
Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor
Peter Ahorukomeye et al.
ELIFE (2019)
Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex
Emiko Uchikawa et al.
ELIFE (2019)
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
Dorothee Liebschner et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2019)
Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs
Tristan Bepler et al.
NATURE METHODS (2019)
UCSF ChimeraX: Meeting modern challenges in visualization and analysis
Thomas D. Goddard et al.
PROTEIN SCIENCE (2018)
MolProbity: More and better reference data for improved all-atom structure validation
Christopher J. Williams et al.
PROTEIN SCIENCE (2018)
Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability
A. K. J. Gradel et al.
JOURNAL OF DIABETES RESEARCH (2018)
Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis
Giovanna Scapin et al.
NATURE (2018)
The signalling conformation of the insulin receptor ectodomain
Felix Weis et al.
NATURE COMMUNICATIONS (2018)
New tools for automated high-resolution cryo-EM structure determination in RELION-3
Jasenko Zivanov et al.
ELIFE (2018)
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
Shawn Q. Zheng et al.
NATURE METHODS (2017)
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
Ali Punjani et al.
NATURE METHODS (2017)
Structural Perspectives of Insulin Receptor Isoform-Selective Insulin Analogs
Jiri Jiracek et al.
FRONTIERS IN ENDOCRINOLOGY (2017)
Venom Insulins of Cone Snails Diversify Rapidly and Track Prey Taxa
Helena Safavi-Hemami et al.
MOLECULAR BIOLOGY AND EVOLUTION (2016)
A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin
John G. Menting et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain
Tristan I. Croll et al.
STRUCTURE (2016)
A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin
John G. Menting et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Specialized insulin is used for chemical warfare by fish-hunting cone snails
Helena Safavi-Hemami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Ligand-binding affinity at the insulin receptor isoform-A and subsequent IR-A tyrosine phosphorylation kinetics are important determinants of mitogenic biological outcomes
Harinda Rajapaksha et al.
FRONTIERS IN ENDOCRINOLOGY (2015)
Aromatic Anchor at an Invariant Hormone-Receptor Interface FUNCTION OF INSULIN RESIDUE B24 WITH APPLICATION TO PROTEIN DESIGN
Vijay Pandyarajan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Protective hinge in insulin opens to enable its receptor engagement
John G. Menting et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone Functionality
Lenka Zakova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
How insulin engages its primary binding site on the insulin receptor
John G. Menting et al.
NATURE (2013)
Characterization of the peptidylglycine α-amidating monooxygenase (PAM) from the venom ducts of neogastropods, Conus bullatus and Conus geographus
Sabah Ul-Hasan et al.
TOXICON (2013)
Insulin X10 revisited: a super-mitogenic insulin analogue
B. F. Hansen et al.
DIABETOLOGIA (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
A Thermodynamic Study of Ligand Binding to the First Three Domains of the Human Insulin Receptor: Relationship between the Receptor α-Chain C-Terminal Peptide and the Site 1 Insulin Mimetic Peptides
John G. Menting et al.
BIOCHEMISTRY (2009)
A chemical method for fast and sensitive detection of DNA synthesis in vivo
Adrian Salic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Structural basis for the lower affinity of the insulin-like growth factors for the insulin receptor
Lisbeth Gauguin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Clustal W and clustal X version 2.0
M. A. Larkin et al.
BIOINFORMATICS (2007)
The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in.the regions governing ligand specificity
Meizhen Lou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
High-affinity adaptors for switchable recognition of histidine-tagged proteins
[Anonymous]
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR
A Denley et al.
MOLECULAR ENDOCRINOLOGY (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
A novel insulin analog with unique properties -: LysB3,GluB29 insulin induces prominent activation of insulin receptor substrate 2, but marginal phosphorylation of insulin receptor substrate 1
I Rakatzi et al.
DIABETES (2003)
Size-distribution analysis of proteins by analytical ultracentrifugation: Strategies and application to model systems
P Schuck et al.
BIOPHYSICAL JOURNAL (2002)
MRBAYES: Bayesian inference of phylogenetic trees
JP Huelsenbeck et al.
BIOINFORMATICS (2001)
High affinity insulin binding by soluble insulin receptor extracellular domain fused to a leucine zipper
PA Hoyne et al.
FEBS LETTERS (2000)
Share Paper
