Journal
NANO RESEARCH
Volume 15, Issue 7, Pages 6430-6437Publisher
TSINGHUA UNIV PRESS
DOI: 10.1007/s12274-022-4306-6
Keywords
antibiotics; specific sensing; metal-organic frameworks; dual sensor; fluorescence quenching
Categories
Funding
- National Natural Science Foundation of China [22038001, 51621003, 22108007]
- Beijing Nova Program [Z211100002121094]
Ask authors/readers for more resources
This study developed an optical sensor system based on metal-organic frameworks (MOFs) for specific detection of prohibited antibiotics in veterinary drugs. The sensor system exhibited high selectivity and sensitivity, enabling rapid and convenient detection of target substances.
The illegal usage of antibiotics as veterinary drugs is an increasing threat for human health. The specific sensing of antibiotics with different toxicity levels is of high challenge, and mainly relies on expensive, time-consuming, and complex instruments. To realize specific sensing by rapid and handy optical sensors, a metal-organic framework (MOF) based dual sensor system is herein developed using two MOF materials BUT-128 and BUT-129 with high sensing selectivity and sensitivity. BUT-128 and BUT-129 exhibit the lowest limit of detection (LOD) towards chloramphenicol and furazolidone among reported MOF sensors. The corresponding dual sensor system with enriched signal readouts realized specific sensing of the strictly forbidden antibiotics (chloramphenicol and nitrofurans) from other regulated veterinary drugs including thiamphenicol, a structural analog of chloramphenicol. Besides, the strategy of this work is expected to flourish the development of optical sensors with high specificity for environment and food safety purposes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available