Related references
Note: Only part of the references are listed.
Review
Biochemistry & Molecular Biology
Martyna Nowak-Perlak et al.
Summary: This review explores the impact of psoriasis on patients' quality of life, discusses the mechanisms involved in the development of the disease and the role of oxidative stress, and considers potential therapeutic options using natural substances.
Article
Biochemistry & Molecular Biology
Elshaymaa I. Elmongy et al.
Summary: This study investigated the phytochemical profile of the root methanol extract of Monterey cypress, as well as its antidiarrheal, antibacterial, and antibiofilm activities. The extract showed potential for treating gastrointestinal tract diseases.
Article
Biochemistry & Molecular Biology
Inga Kwiecien et al.
Summary: Studies have demonstrated the antioxidant activity and non-toxicity of Scutellaria lateriflora microshoot extract. Feeding the microshoots with phenylalanine was found to be the most effective strategy to enhance the production of flavonoids and verbascoside, resulting in a high antioxidant content.
Review
Biochemistry & Molecular Biology
Sara Motyka et al.
Summary: Chia seeds are a health food with rich chemical composition and valuable nutritional properties. They have cardioprotective, hypotensive, anti-diabetic, and anti-atherosclerotic effects. Chia seeds also have neuroprotective, hepatoprotective, anti-inflammatory, and antioxidant properties, making them effective in preventing civilization diseases.
Article
Biochemistry & Molecular Biology
Wonmin Ko et al.
Summary: The study revealed that compounds 3 and 4 from the methanolic extract of Morus alba bark exhibit significant anti-inflammatory effects by inhibiting nitric oxide production, reducing the release of inflammatory factors, and regulating the anti-inflammatory effects through activated HO-1. These compounds may serve as potential candidates for the development of therapeutic and preventive agents for inflammatory diseases.
Article
Biochemistry & Molecular Biology
Mi-Gyeong Gwon et al.
Summary: 6-Shogaol, a major component of ginger, shows potential therapeutic effects against cisplatin-induced acute kidney injury by alleviating oxidative stress, modulating cell death, and suppressing inflammation.
Article
Biochemistry & Molecular Biology
Barbara Thiem et al.
Summary: Through this study, a reliable protocol for efficient micropropagation of uniform L. borealis L. var. borealis plantlets was established, with agitated shoot cultures in liquid media proving to be the most effective system. The presence of iridoids and triterpenoid saponins in this species was confirmed for the first time, allowing for further research on the biological activity and phytochemical profile.
Article
Biochemistry & Molecular Biology
Claudia Delgado et al.
Summary: Research on extracts from Hymenaea courbaril L. revealed that the main compound caryophyllene oxide can induce apoptosis in prostate cancer cells with low toxicity, and has minimal impact on normal cells. This compound causes depolarization of the mitochondrial membrane and results in various morphological changes and shifts in apoptotic proteins and caspases.
Article
Biochemistry & Molecular Biology
Abhijit Ghosh et al.
Summary: Cytogenetic analysis is crucial for evaluating the effects of mutagens and anti-mutagens on genetic materials. This study demonstrates the protective effect of Morus alba root bark extract against cyclophosphamide-induced somatic and germinal cell damage in male rats, likely due to its antioxidant properties.
Article
Biochemistry & Molecular Biology
Askhat Sabitov et al.
Summary: This study found that the extract from Rosa platyacantha flower buds showed significant antioxidant and tyrosinase inhibitory potential. The extract exhibited cytotoxicity against human melanoma cells but less toxicity for noncancerous skin cells. Analysis of the extract's fractions revealed the likely compounds responsible for its biological activities.
Article
Biochemistry & Molecular Biology
Natalia Kleczek et al.
Summary: The study assessed the cytotoxic activity of selected C. divaricatum germacranolides derivatives towards cancer and normal cell lines, as well as the anti-inflammatory effect of the compounds by measuring the release of proinflammatory cytokines/chemokines by lipopolysaccharide-stimulated human neutrophils.
Article
Biochemistry & Molecular Biology
Marta Klimek-Szczykutowicz et al.
Summary: The study showed that precursor feeding using L-phenylalanine and L-tryptophan in Nasturtium officinale microshoot cultures significantly increased the production of glucosinolates, flavonoids, and polyphenols, and also had a positive impact on photosynthetic pigments.
Article
Biochemistry & Molecular Biology
Wei Li et al.
Summary: Six lignols, including two new compounds, were isolated from Platycodon grandiflorum root. These compounds showed anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines in murine macrophage cells. Further investigation into the potential anti-inflammatory activity of these compounds is warranted.
Article
Biochemistry & Molecular Biology
Katarzyna Papierska et al.
Summary: The study evaluated the modulation of Nrf2, NF-kappa B and STAT3 signaling pathways in colorectal cancer cells by lichen-derived secondary metabolites. Physodic and salazinic acids showed the highest activity against CRC cells, affecting Nrf2 activation and gene expression while inducing opposite effects on NF-kappa B and STAT3 pathways. Caperatic acid had the most impact on Wnt/beta-catenin, while salazinic acid was the most potent modulator of Nrf2, NF-kappa B and STAT3 pathways. Physodic acid seemed to affect all investigated pathways.
