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Coffee Chlorogenic Acids Incorporation for Bioactivity Enhancement of Foods: A Review

Journal

MOLECULES
Volume 27, Issue 11, Pages -

Publisher

MDPI
DOI: 10.3390/molecules27113400

Keywords

chlorogenic acids; coffee; 5CQA; functional foods; biological activity

Funding

  1. United States, Department of Agriculture (USDA) [OKL03091]
  2. National Institute of Food and Agriculture
  3. Oklahoma Agricultural Experiment Station, Oklahoma State University

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The demand for foods with high antioxidant capacity is growing, and research on chlorogenic acids (CGAs) from green coffee, which is the most abundant source, continues to increase. CGAs have been associated with various health benefits, such as antioxidant, antiviral, antibacterial, anticancer, and anti-inflammatory activities, as well as reducing the risk of cardiovascular diseases, type 2 diabetes, and Alzheimer's disease. Adding CGAs extracts to different food matrices has been found to increase anthocyanin and antioxidant activity, improving the functionality of foods.
The demand of foods with high antioxidant capacity have increased and research on these foods continues to grow. This review is focused on chlorogenic acids (CGAs) from green coffee, which is the most abundant source. The main CGA in coffee is 5-O-caffeoylquinic acid (5-CQA). Coffee extracts are currently the most widely used source to enhance the antioxidant activity of foods. Due to the solubility of CGAs, their extraction is mainly performed with organic solvents. CGAs have been associated with health benefits, such as antioxidant, antiviral, antibacterial, anticancer, and anti-inflammatory activity, and others that reduce the risk of cardiovascular diseases, type 2 diabetes, and Alzheimer's disease. However, the biological activities depend on the stability of CGAs, which are sensitive to pH, temperature, and light. The anti-inflammatory activity of 5-CQA is attributed to reducing the proinflammatory activity of cytokines. 5-CQA can negatively affect colon microbiota. An increase in anthocyanins and antioxidant activity was observed when CGAs extracts were added to different food matrices such as dairy products, coffee drinks, chocolate, and bakery products. The fortification of foods with coffee CGAs has the potential to improve the functionality of foods.

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