Cardiovascular Disease and Possible Ways in Which Lycopene Acts as an Efficient Cardio-Protectant against Different Cardiovascular Risk Factors

Foods rich in antioxidants such as lycopene have a major role in maintaining cardiac health. Lycopene, 80% of which can be obtained by consuming a common vegetable such as tomato, can prevent the disturbances that contribute to cardiovascular disease (CVD). The present work begins with a brief introduction to CVD and lycopene and its various properties such as bioavailability, pharmacokinetics, etc. In this review, the potential cardio-protective effects of lycopene that reduce the progression of CVD and thrombotic complications are detailed. Further, the protective effects of lycopene including in vitro, in vivo and clinical trials conducted on lycopene for CVD protective effects are explained. Finally, the controversial aspect of lycopene as a protective agent against CVD and toxicity are also mentioned.

Automated summary

Lycopene, a powerful antioxidant found in foods like tomatoes, plays a significant role in maintaining cardiac health by reducing the progression of cardiovascular disease and thrombotic complications. This review explores the potential cardio-protective effects of lycopene, including in vitro, in vivo, and clinical trials, as well as its bioavailability and pharmacokinetics. However, the protective role of lycopene against cardiovascular disease and its toxicity remain controversial.