4.6 Letter

The route of SARS-CoV-2 to brain infection: have we been barking up the wrong tree?

Journal

MOLECULAR NEURODEGENERATION
Volume 17, Issue 1, Pages -

Publisher

BMC
DOI: 10.1186/s13024-022-00529-9

Keywords

COVID-19; SARS-CoV-2; Brain infection; ACE2; Olfactory system; Nervus terminalis; Omicron; TMPRSS2

Categories

Funding

  1. National Institutes of Health [GM103554]

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Recent research suggests that the SARS-CoV-2 virus may infect the brain through the nervus terminalis instead of the olfactory nerve.
This letter draws attention to recent work supporting the notion that the SARS-CoV-2 virus may use the nervus terminalis rather than the olfactory nerve as a shortcut route from the nasal cavity to infect the brain.

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