Related references
Note: Only part of the references are listed.Diabetes-Alzheimer's Disease Link: Targeting Mitochondrial Dysfunction and Redox Imbalance
Cristina Carvalho et al.
ANTIOXIDANTS & REDOX SIGNALING (2021)
The function of SUMOylation and its crucial roles in the development of neurological diseases
Xu Chen et al.
FASEB JOURNAL (2021)
Alzheimer's disease
Philip Scheltens et al.
LANCET (2021)
Mitochondrial Dysfunction and Oxidative Stress in Alzheimer's Disease
Afzal Misrani et al.
FRONTIERS IN AGING NEUROSCIENCE (2021)
Aggregated Tau-PHF6 (VQIVYK) Potentiates NLRP3 Inflammasome Expression and Autophagy in Human Microglial Cells
Chinmaya Panda et al.
CELLS (2021)
Pyridoxine/pyridoxamine 5′-phosphate oxidase (Sgll/PNPO) is important for DNA integrity and glucose homeostasis maintenance in Drosophila
Elisa Mascolo et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2020)
Obesity and Diabetes Mediated Chronic Inflammation: A Potential Biomarker in Alzheimer's Disease
Md Shahjalal Hossain Khan et al.
JOURNAL OF PERSONALIZED MEDICINE (2020)
Insights from Drosophila melanogaster model of Alzheimer's disease
Nguyen Trong Tue et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2020)
Biomarkers for Alzheimer's Disease
Leonardo Guzman-Martinez et al.
CURRENT ALZHEIMER RESEARCH (2019)
Alzheimer's disease: pathogenesis, diagnostics, and therapeutics
Sneham Tiwari et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)
Similar effects of high-fructose and high-glucose feeding in a Drosophila model of obesity and diabetes
Laura Palanker Musselman et al.
PLOS ONE (2019)
Simple techniques to study multifaceted diabesity in the fly model
Nibedita Nayak et al.
TOXICOLOGY MECHANISMS AND METHODS (2019)
Neuroinflammation as a Common Feature of Neurodegenerative Disorders
Leonardo Guzman-Martinez et al.
FRONTIERS IN PHARMACOLOGY (2019)
An evaluation of Drosophila as a model system for studying tauopathies such as Alzheimer's disease
Lovesha Sivanantharajah et al.
JOURNAL OF NEUROSCIENCE METHODS (2019)
A high-sugar diet affects cellular and humoral immune responses in Drosophila
Shichao Yu et al.
EXPERIMENTAL CELL RESEARCH (2018)
Sweet Mitochondria: A Shortcut to Alzheimer's Disease
Paula I. Moreira
JOURNAL OF ALZHEIMERS DISEASE (2018)
Mitochondria and Mitochondrial Cascades in Alzheimer's Disease
Russell H. Swerdlow
JOURNAL OF ALZHEIMERS DISEASE (2018)
Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications
Geert Jan Biessels et al.
NATURE REVIEWS ENDOCRINOLOGY (2018)
Amyloid toxicity in Alzheimer's disease
Allison B. Reiss et al.
REVIEWS IN THE NEUROSCIENCES (2018)
Drosophila melanogaster as a Model for Diabetes Type 2 Progression
Jessica P. Alvarez-Rendon et al.
BIOMED RESEARCH INTERNATIONAL (2018)
Research Progress on Non-Drug Treatment for Blood Glucose Control of Type 2 Diabetes Mellitus
Wei Jun-ping et al.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2018)
Longevity extension in Drosophila through gut-brain communication
Susan Westfall et al.
SCIENTIFIC REPORTS (2018)
Type 2 Diabetes Mellitus and Alzheimer's Disease: Role of Insulin Signalling and Therapeutic Implications
Andrea Tumminia et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Prevalence of type 2 diabetes and its complications in India and economic costs to the nation
R. Pradeepa et al.
EUROPEAN JOURNAL OF CLINICAL NUTRITION (2017)
Promoting Glucose Transporter-4 vesicle Trafficking along Cytoskeletal Tracks: PAK-Ing Them Out
Ragadeepthi Tunduguru et al.
FRONTIERS IN ENDOCRINOLOGY (2017)
Muscle Directs Diurnal Energy Homeostasis through a Myokine-Dependent Hormone Module in Drosophila
Xiao Zhao et al.
CURRENT BIOLOGY (2017)
Overexpression of hsp27 Rescued Neuronal Cell Death and Reduction in Life- and Health-Span in Drosophila melanogaster Against Prolonged Exposure to Dichlorvos
Ashutosh Pandey et al.
MOLECULAR NEUROBIOLOGY (2016)
Battling Alzheimer's Disease: Targeting SUMOylation-Mediated Pathways
Wagner Carbolin Martins et al.
NEUROCHEMICAL RESEARCH (2016)
Executive functions in patients with Alzheimer's disease, type 2 diabetes mellitus patients and cognitively healthy older adults
Maria Teresa Redondo et al.
EXPERIMENTAL GERONTOLOGY (2016)
Diabetes mellitus and its complications in India
Ranjit Unnikrishnan et al.
NATURE REVIEWS ENDOCRINOLOGY (2016)
Diabetes and Alzheimer's disease crosstalk
David Baglietto-Vargas et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2016)
SUMO-Modification of the La Protein Facilitates Binding to mRNA In Vitro and in Cells
Venkatesh Kota et al.
PLOS ONE (2016)
Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer's disease with cerebrovascular disease
Xavier Gallart-Palau et al.
MOLECULAR BRAIN (2016)
Intensive Treatment and Severe Hypoglycemia Among Adults With Type 2 Diabetes
Rozalina G. McCoy et al.
JAMA INTERNAL MEDICINE (2016)
Pancreatic β-cell identity, glucose sensing and the control of insulin secretion
Guy A. Rutter et al.
BIOCHEMICAL JOURNAL (2015)
Genetic diagnosis and prognosis of Alzheimer's disease: challenges and opportunities
Christiane Reitz
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2015)
Energy Homeostasis Control in Drosophila Adipokinetic Hormone Mutants
Martina Galikova et al.
GENETICS (2015)
Hyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivo
Shannon L. Macauley et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy
Marzia Perluigi et al.
NEUROBIOLOGY OF DISEASE (2015)
Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein
Michel Goedert
SCIENCE (2015)
Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism
Rupali Ugrankar et al.
NATURE COMMUNICATIONS (2015)
Energy Homeostasis Control in Drosophila Adipokinetic Hormone Mutants
Martina Galikova et al.
GENETICS (2015)
SUMOylation: Novel Neuroprotective Approach for Alzheimer's Disease?
Juliana B. Hoppe et al.
AGING AND DISEASE (2015)
Regulation of autophagy by amino acids and MTOR-dependent signal transduction
Alfred J. Meijer et al.
AMINO ACIDS (2015)
SUMO1 promotes Aβ production via the modulation of autophagy
Sun-Jung Cho et al.
AUTOPHAGY (2015)
Brain metabolic dysfunction at the core of Alzheimer's disease
Suzanne M. de la Monte et al.
BIOCHEMICAL PHARMACOLOGY (2014)
The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
David Heras-Sandoval et al.
CELLULAR SIGNALLING (2014)
Insulin-Degrading Enzyme: A Link Between Alzheimer's and Type 2 Diabetes Mellitus
Rizwanul Haque et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2014)
Why do brains need tau (MAPT)?
Linda A. Amos
FEBS JOURNAL (2014)
Biomarkers for Preclinical Alzheimer's Disease
Chen-Chen Tan et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease
Shichun Tu et al.
MOLECULAR NEURODEGENERATION (2014)
Dietary advanced glycation end products are associated with decline in memory in young elderly
Rebecca K. West et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2014)
SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination
Hong-Bin Luo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans
Weijing Cai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
A Nutritional Conditional Lethal Mutant Due to Pyridoxine 5′-Phosphate Oxidase Deficiency in Drosophila melanogaster
Wanhao Chi et al.
G3-GENES GENOMES GENETICS (2014)
Hypoglycemia Is Independently Associated with Multidimensional Impairment in Elderly Diabetic Patients
A. Pilotto et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Amyloid-β and Tau The Trigger and Bullet in Alzheimer Disease Pathogenesis
George S. Bloom
JAMA NEUROLOGY (2014)
Increased expression of the receptor for advanced glycation end products in neurons and astrocytes in a triple transgenic mouse model of Alzheimer's disease
Bo-Ryoung Choi et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2014)
Tau protein kinases: Involvement in Alzheimer's disease
Ludovic Martin et al.
AGEING RESEARCH REVIEWS (2013)
Insulin Has Multiple Antiamyloidogenic Effects on Human Neuronal Cells
Giuseppe Pandini et al.
ENDOCRINOLOGY (2013)
Insulin, cognition, and dementia
Brenna Cholerton et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2013)
The SLC2 (GLUT) family of membrane transporters
Mike Mueckler et al.
MOLECULAR ASPECTS OF MEDICINE (2013)
SUMO1 modulates Aβ generation via BACE1 accumulation
Sang-Moon Yun et al.
NEUROBIOLOGY OF AGING (2013)
A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease
Yoshihiro Kashiwaya et al.
NEUROBIOLOGY OF AGING (2013)
Hox Genes: Choreographers in Neural Development, Architects of Circuit Organization
Polyxeni Philippidou et al.
NEURON (2013)
Insulin Regulates Glut4 Confinement in Plasma Membrane Clusters in Adipose Cells
Vladimir A. Lizunov et al.
PLOS ONE (2013)
The importance of tau phosphorylation for neurodegenerative diseases
Wendy Noble et al.
FRONTIERS IN NEUROLOGY (2013)
Alzheimer culprits: Cellular crossroads and interplay
Sylvie Claeysen et al.
CELLULAR SIGNALLING (2012)
Locus-specific mutation databases for neurodegenerative brain diseases
Marc Cruts et al.
HUMAN MUTATION (2012)
The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE
Rita J. Guerreiro et al.
NEUROBIOLOGY OF AGING (2012)
Mechanisms Underlying Insulin Deficiency-Induced Acceleration of β-Amyloidosis in a Mouse Model of Alzheimer's Disease
Latha Devi et al.
PLOS ONE (2012)
Induction of Neuronal Death by Microglial AGE-Albumin: Implications for Alzheimer's Disease
Kyunghee Byun et al.
PLOS ONE (2012)
Assessing family caregiver skill in managing behavioral symptoms of Alzheimer's disease
Carol J. Farran et al.
AGING & MENTAL HEALTH (2011)
Alzheimer's Association Report 2011 Alzheimer's disease facts and figures
ALZHEIMERS & DEMENTIA (2011)
Functional Screening of Alzheimer Pathology Genome-wide Association Signals in Drosophila
Joshua M. Shulman et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
Effects of Insulin on Brain Glucose Metabolism in Impaired Glucose Tolerance
Jussi Hirvonen et al.
DIABETES (2011)
A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila
Laura Palanker Musselman et al.
DISEASE MODELS & MECHANISMS (2011)
Biology and pathophysiology of the amyloid precursor protein
Hui Zheng et al.
MOLECULAR NEURODEGENERATION (2011)
Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals
Michal Schnaider Beeri et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2011)
Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease
Velandai Srikanth et al.
NEUROBIOLOGY OF AGING (2011)
Profiles of SUMO and ubiquitin conjugation in an Alzheimer's disease model
Laura E. McMillan et al.
NEUROSCIENCE LETTERS (2011)
Characterization of a Drosophila Alzheimer's Disease Model: Pharmacological Rescue of Cognitive Defects
Ranjita Chakraborty et al.
PLOS ONE (2011)
Molecular mechanisms of metabolic regulation by insulin in Drosophila
Aurelio A. Teleman
BIOCHEMICAL JOURNAL (2010)
Targets and consequences of protein SUMOylation in neurons
Kevin A. Wilkinson et al.
BRAIN RESEARCH REVIEWS (2010)
Partial ablation of adult Drosophila insulin-producing neurons modulates glucose homeostasis and extends life span without insulin resistance
Aaron Haselton et al.
CELL CYCLE (2010)
The global burden of diabetes and its complications: an emerging pandemic
Susan van Dieren et al.
EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION (2010)
Role of Mitochondrial Amyloid-beta in Alzheimer's Disease
John Xi Chen et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Glucose increases activity and Ca2+ in insulin-producing cells of adult Drosophila
Orsolya Kreneisz et al.
NEUROREPORT (2010)
Preliminary evidence that polymorphisms in dopamine-related transcription factors LMX1A, LMX1B and PITX3 are associated with schizophrenia
Olle Bergman et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2010)
Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides
Sebastian Groenke et al.
PLOS GENETICS (2010)
d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila
Robert Wessells et al.
AGING CELL (2009)
Drosophila melanogaster as a Model Organism of Brain Diseases
Astrid Jeibmann et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2009)
Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease
Henrik Zetterberg et al.
ARCHIVES OF NEUROLOGY (2008)
SUMO-1 immunoreactivity co-localizes with phospho-Tau in APP transgenic mice but not in mutant Tau transgenic mice
Kaoru Takahashi et al.
NEUROSCIENCE LETTERS (2008)
Aβ42 Mutants with Different Aggregation Profiles Induce Distinct Pathologies in Drosophila
Koichi Iijima et al.
PLOS ONE (2008)
Concepts in sumoylation: a decade on
Ruth Geiss-Friedlander et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Diabetic larvae and obese flies -: Emerging studies of metabolism in Drosophila
Keith D. Baker et al.
CELL METABOLISM (2007)
Affinity chromatography of native SUMO proteins using His-tagged recombinant UBC9 bound to Co2+-charged talon resin
Kurt M. Bohren et al.
PROTEIN EXPRESSION AND PURIFICATION (2007)
Modification in reverse: the SUMO proteases
Debaditya Mukhopadhyay et al.
TRENDS IN BIOCHEMICAL SCIENCES (2007)
Modulation of Aβ generation by small ubiquitin-like modifiers does not require conjugation to target proteins
Veronique Dorval et al.
BIOCHEMICAL JOURNAL (2007)
SUMO on the road to neurodegeneration
Veronique Dorval et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in bilateria
Alexandru S. Denes et al.
CELL (2007)
The presenilin hypothesis of Alzheimer's disease: Evidence for a loss-of-function pathogenic mechanism
Jie Shen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Sumoylation in neurons: nuclear and synaptic roles?
Astrid Scheschonka et al.
TRENDS IN NEUROSCIENCES (2007)
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
Carlo Ballatore et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Drosophila melanogaster neurobiology, neuropharmacology, and how the fly can inform central nervous system drug discovery
Charles D. Nichols
PHARMACOLOGY & THERAPEUTICS (2006)
A century of Alzheimer's disease
Michel Goedert et al.
SCIENCE (2006)
Type 1 diabetes: pathogenesis and prevention
Kathleen M. Gillespie
CANADIAN MEDICAL ASSOCIATION JOURNAL (2006)
A calcium-regulated MEF2 surnoylation switch controls postsynaptic differentiation
A Shalizi et al.
SCIENCE (2006)
Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease:: review and hypothesis
WQ Qiu et al.
NEUROBIOLOGY OF AGING (2006)
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands
SJ Broughton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Hemolymph sugar homeostasis and starvation-induced hyperactivity affected by genetic manipulations of the adipokinetic hormone-encoding gene in Drosophila melanogaster
GH Lee et al.
GENETICS (2004)
Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila
I Greeve et al.
JOURNAL OF NEUROSCIENCE (2004)
Modulation of memory by insulin and glucose: neuropsychological observations in Alzheimer's disease
GS Watson et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Conserved mechanisms of glucose sensing and regulation by Drosophila corpora cardiaca cells
SK Kim et al.
NATURE (2004)
Tau phosphorylation in neuronal cell function and dysfunction
GVW Johnson et al.
JOURNAL OF CELL SCIENCE (2004)
Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases
DJ Selkoe
NATURE CELL BIOLOGY (2004)
Reconstitution of γ-secretase activity
D Edbauer et al.
NATURE CELL BIOLOGY (2003)
Insulin-responsive glucose transporters - GLUT8 and GLUT4 are expressed in the developing mammalian brain
R Sankar et al.
MOLECULAR BRAIN RESEARCH (2002)
Ablation of insulin-producing neurons in flies: Growth and diabetic phenotypes
EJ Rulifson et al.
SCIENCE (2002)
The intracellular domain of the β-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a Notch-like manner
WT Kimberly et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The effect of insulin on in vivo cerebral glucose concentrations and rates of glucose transport/metabolism in humans
ER Seaquist et al.
DIABETES (2001)
The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members
HG Joost et al.
MOLECULAR MEMBRANE BIOLOGY (2001)
The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SURIO-1 modification
DA Sampson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting
MS Rodriguez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Obesity and insulin resistance
BB Kahn et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Comparative genomics of the eukaryotes
GM Rubin et al.
SCIENCE (2000)
Share Paper
