Related references
Note: Only part of the references are listed.STAT3 Signaling in Breast Cancer: Multicellular Actions and Therapeutic Potential
Sarah Q. To et al.
CANCERS (2022)
STAT3 and its targeting inhibitors in osteosarcoma
Yun Liu et al.
CELL PROLIFERATION (2021)
LGR5 induces β-catenin activation and augments tumour progression by activating STAT3 in human intrahepatic cholangiocarcinoma
Keishi Kawasaki et al.
LIVER INTERNATIONAL (2021)
Tumor-associated neutrophils and macrophages interaction contributes to intrahepatic cholangiocarcinoma progression by activating STAT3
Zhengjun Zhou et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021)
Role of JAK/STAT in Interstitial Lung Diseases; Molecular and Cellular Mechanisms
Paula Montero et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Recent Update on Development of Small-Molecule STAT3 Inhibitors for Cancer Therapy: From Phosphorylation Inhibition to Protein Degradation
Jinyun Dong et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
The role of JAK/STAT signaling pathway and its inhibitors in diseases
Ping Xin et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2020)
Molecular classification and therapeutic targets in extrahepatic cholangiocarcinoma
Robert Montal et al.
JOURNAL OF HEPATOLOGY (2020)
STAT3 transcription factor as target for anti-cancer therapy
Aliaa M. Mohassab et al.
PHARMACOLOGICAL REPORTS (2020)
Intrahepatic cholangiocarcinoma induced M2-polarized tumor-associated macrophages facilitate tumor growth and invasiveness
Hui Yuan et al.
CANCER CELL INTERNATIONAL (2020)
Activating mutations of STAT3: Impact on human growth
Mariana Gutierrez
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2020)
Tumour-associated neutrophils in patients with cancer
Merav E. Shaul et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2019)
Fibroblastic FAP promotes intrahepatic cholangiocarcinoma growth via MDSCs recruitment
Yuli Lin et al.
NEOPLASIA (2019)
The role of STAT3 in leading the crosstalk between human cancers and the immune system
Yu Wang et al.
CANCER LETTERS (2018)
STAT3 overexpression promotes metastasis in intrahepatic cholangiocarcinoma and correlates negatively with surgical outcome
Yang Xin-wei et al.
ONCOTARGET (2017)
Improving patient selection for selective internal radiation therapy of intra-hepatic cholangiocarcinoma: A meta-regression study
Alessandro Cucchetti et al.
LIVER INTERNATIONAL (2017)
Tumor regulation of the tissue environment in the liver
Tobias Eggert et al.
PHARMACOLOGY & THERAPEUTICS (2017)
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway
Xiongyan Wu et al.
ONCOTARGET (2017)
JAK-STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects (vol 77, pg 521, 2017)
Shubhasree Banerjee et al.
DRUGS (2017)
The Opposing Function of STAT3 as an Oncoprotein and Tumor Suppressor Is Dictated by the Expression Status of STAT3β in Esophageal Squamous Cell Carcinoma
Hai-Feng Zhang et al.
CLINICAL CANCER RESEARCH (2016)
Serum-resistant CpG-STAT3 decoy for targeting survival and immune checkpoint signaling in acute myeloid leukemia
Qifang Zhang et al.
BLOOD (2016)
Evaluation and management of intrahepatic and extrahepatic cholangiocarcinoma
Nestor F. Esnaola et al.
CANCER (2016)
FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling
Xuguang Yang et al.
CANCER RESEARCH (2016)
Role of the tumor microenvironment in pancreatic adenocarcinoma
Xian-Jun Sun et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2016)
IL-6 pathway in the liver: From physiopathology to therapy
Dirk Schmidt-Arras et al.
JOURNAL OF HEPATOLOGY (2016)
Forty-Year Trends in Cholangiocarcinoma Incidence in the US: Intrahepatic Disease on the Rise
Supriya K. Saha et al.
ONCOLOGIST (2016)
The STAT3 pathway as a therapeutic target in head and neck cancer: Barriers and innovations
Jessica L. Geiger et al.
ORAL ONCOLOGY (2016)
STAT3 in the systemic inflammation of cancer cachexia
Teresa A. Zimmers et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2016)
Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma
Uddalak Bharadwaj et al.
ONCOTARGET (2016)
Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies
A. L. Wong et al.
ANNALS OF ONCOLOGY (2015)
Phase I study of OPB-51602, an oral inhibitor of signal transducer and activator of transcription 3, in patients with relapsed/refractory hematological malignancies
Michinori Ogura et al.
CANCER SCIENCE (2015)
Modulation of STAT3 and STAT5 activity rectifies the imbalance of Th17 and Treg cells in patients with acute coronary syndrome
Yingxia Zheng et al.
CLINICAL IMMUNOLOGY (2015)
Phase 1 and pharmacological trial of OPB-31121, a signal transducer and activator of transcription-3 inhibitor, in patients with advanced hepatocellular carcinoma
Takuji Okusaka et al.
HEPATOLOGY RESEARCH (2015)
Signal Transducer and Activator of Transcription 4 in Liver Diseases
Yan Wang et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2015)
Tyrosine Phosphorylation of the Lyn Src Homology 2 (SH2) Domain Modulates Its Binding Affinity and Specificity
Lily L. Jin et al.
MOLECULAR & CELLULAR PROTEOMICS (2015)
Expression and activation of EGFR and STAT3 during the multistage carcinogenesis of intrahepatic cholangiocarcinoma induced by 3′-methyl-4 dimethylaminoazobenzene in rats
Fan Zhang et al.
JOURNAL OF TOXICOLOGIC PATHOLOGY (2015)
Phase I Study of OPB-31121, an Oral STAT3 Inhibitor, in Patients with Advanced Solid Tumors
Do-Youn Oh et al.
CANCER RESEARCH AND TREATMENT (2015)
Inhibition of IL-6/STAT3 axis and targeting Axl and Tyro3 receptor tyrosine kinases by apigenin circumvent taxol resistance in ovarian cancer cells
Young-Ah Suh et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2015)
Analysis of Indoleamine 2-3 Dioxygenase (IDO) and EGFR Co-expression in Breast Cancer Tissue by Immunohistochemistry
Wei-Wei Bi et al.
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION (2014)
The prognostic importance of jaundice in surgical resection with curative intent for gallbladder cancer
Xin-wei Yang et al.
BMC CANCER (2014)
Phase 1, open-label, dose-escalation, and pharmacokinetic study of STAT3 inhibitor OPB-31121 in subjects with advanced solid tumors
Johanna C. Bendell et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2014)
The IL-6/JAK/STAT3 pathway: Potential therapeutic strategies in treating colorectal cancer (Review)
Shu-Wei Wang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition
Audrey Claperon et al.
JOURNAL OF HEPATOLOGY (2014)
Fibroblast Activation Protein (FAP) Is Essential for the Migration of Bone Marrow Mesenchymal Stem Cells through RhoA Activation
Kuei-Min Chung et al.
PLOS ONE (2014)
ErbB/HER protein-tyrosine kinases: Structures and small molecule inhibitors
Robert Roskoski
PHARMACOLOGICAL RESEARCH (2014)
Structure and function of LGR5: An enigmatic G-protein coupled receptor marking stem cells
Kaavya Krishna Kumar et al.
PROTEIN SCIENCE (2014)
Understanding fibroblast activation protein (FAP): Substrates, activities, expression and targeting for cancer therapy
Elizabeth J. Hamson et al.
PROTEOMICS CLINICAL APPLICATIONS (2014)
Bipolar/rod-shaped microglia are proliferating microglia with distinct M1/M2 phenotypes
Wing Yip Tam et al.
SCIENTIFIC REPORTS (2014)
Genetic Interactions of STAT3 and Anticancer Drug Development
Bingliang Fang
CANCERS (2014)
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
Hua Yu et al.
NATURE REVIEWS CANCER (2014)
OPB-31121, a novel small molecular inhibitor, disrupts the JAK2/STAT3 pathway and exhibits an antitumor activity in gastric cancer cells
Mi-Jung Kim et al.
CANCER LETTERS (2013)
Hepatic Myofibroblasts Promote the Progression of Human Cholangiocarcinoma Through Activation of Epidermal Growth Factor Receptor
Audrey Claperon et al.
HEPATOLOGY (2013)
Inhibitory effects of STAT3 decoy oligodeoxynucleotides on human epithelial ovarian cancer cell growth in vivo
Xiaolei Zhang et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2013)
Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies
D. Sia et al.
ONCOGENE (2013)
Icaritin Inhibits JAK/STAT3 Signaling and Growth of Renal Cell Carcinoma
Shasha Li et al.
PLOS ONE (2013)
A novel STAT inhibitor, OPB-31121, has a significant antitumor effect on leukemia with STAT-addictive oncokinases
F. Hayakawa et al.
BLOOD CANCER JOURNAL (2013)
Reciprocal roles of STAT3 and STAT5 in nasal polyposis
Xiao-Qiang Wang et al.
AMERICAN JOURNAL OF OTOLARYNGOLOGY (2012)
Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of treg cells
Ji Hyeon Ju et al.
ARTHRITIS AND RHEUMATISM (2012)
Expression and Clinical Significance of STAT3, P-STAT3, and VEGF-C in Small Cell Lung Cancer
Xue Zhao et al.
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION (2012)
The macrophage response towards LPS and its control through the p38MAPK-STAT3 axis
Johannes G. Bode et al.
CELLULAR SIGNALLING (2012)
Tissue microarray-based study of patients with lymph node-positive breast cancer shows tyrosine phosphorylation of signal transducer and activator of transcription 3 (tyrosine705-STAT3) is a marker of good prognosis
Amir Sonnenblick et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2012)
Evaluation of Risk Factors and Clinicopathologic Features for Intrahepatic Cholangiocarcinoma in Southern China: A Possible Role of Hepatitis B Virus
Ning-fu Peng et al.
ANNALS OF SURGICAL ONCOLOGY (2011)
Myofibroblast-Derived PDGF-BB Promotes Hedgehog Survival Signaling in Cholangiocarcinoma Cells
Christian D. Fingas et al.
HEPATOLOGY (2011)
Potent and Selective Phosphopeptide Mimetic Prodrugs Targeted to the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 3
Pijus K. Mandal et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Stat3: linking inflammation to epithelial cancer - more than a gut feeling?
Andrew Jarnicki et al.
CELL DIVISION (2010)
Expression of activated signal transducer and activator of transcription-3 predicts poor prognosis in cervical squamous-cell carcinoma
S. Takemoto et al.
BRITISH JOURNAL OF CANCER (2009)
WNT signaling in stem cell biology and regenerative medicine
Masaru Katoh
CURRENT DRUG TARGETS (2008)
Signal transducer and activator of transcription 3 activation is associated with bladder cancer cell growth and survival
Chun-Liang Chen et al.
MOLECULAR CANCER (2008)
Activation of Signal Transducers and Activators of Transcription 3 and Overexpression of its Target Gene CyclinD1 in Laryngeal Carcinomas
Bin Liu et al.
LARYNGOSCOPE (2008)
Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice
Xulong Zhang et al.
BMC CANCER (2007)
Risk factors for cholangiocarcinoma
Tamir Ben-Menachem
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2007)
WNT signaling pathway and stem cell signaling network
Masuko Katoh et al.
CLINICAL CANCER RESEARCH (2007)
Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
Hua Yu et al.
NATURE REVIEWS IMMUNOLOGY (2007)
Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-κB and -MAPK signaling pathways
T Yokoyama et al.
LIVER INTERNATIONAL (2006)
Possible regulation of migration of intrahepatic cholangiocarcinoma cells by interaction of CXCR4 expressed in carcinoma cells with tumor necrosis factor-α and stromal-derived factor-1 released in stroma
S Ohira et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
An oligonucleotide decoy for Stat3 activates the immune response of macrophages to breast cancer
ZK Sun et al.
IMMUNOBIOLOGY (2006)
Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer
EB Haura et al.
CLINICAL CANCER RESEARCH (2005)
Wnt signaling in the intestinal epithelium: from endoderm to cancer
A Gregorieff et al.
GENES & DEVELOPMENT (2005)
In vivo antitumor efficacy of STAT3 blockade using a transcription factor decoy approach:: implications for cancer therapy
SC Xi et al.
ONCOGENE (2005)
Nuclear factor-κB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis
AC Bharti et al.
BLOOD (2004)
Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis
KS Chan et al.
CANCER RESEARCH (2004)
The stats of cancer - New molecular targets come of age
H Yu et al.
NATURE REVIEWS CANCER (2004)
Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis
KS Chan et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells
N Kanda et al.
ONCOGENE (2004)
Fibroblast activation protein: Differential expression and serine protease activity in reactive stromal fibroblasts of melanocytic skin tumors
MA Huber et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2003)
Constitutive activation of Stat3α in brain tumors:: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2)
LK Schaefer et al.
ONCOGENE (2002)
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation
J Turkson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Share Paper
