4.8 Editorial Material

Dangerous RNA links pave the way to glioblastoma

Journal

MOLECULAR CELL
Volume 82, Issue 10, Pages 1783-1785

Publisher

CELL PRESS
DOI: 10.1016/j.molcel.2022.04.029

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Funding

  1. European Research Council under the European Union's Horizon 2020 research and innovation program [StG-2016_GENOMIS_715727]

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A new study demonstrates the connection between two long non-coding RNAs and the transcriptional activation of the therapeutic target miR-10b in glioblastoma multiforme by linking a distal enhancer to the HOXD3/D4/miR-10b gene promoter.
A new study by Deforzh et al. (2022) demonstrates how two long non-coding RNAs (lncRNAs) link a distal enhancer to the HOXD3/D4/miR-10b gene promoter, leading to transcriptional activation of the therapeutic target miR-10b in glioblastoma multiforme.

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