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Beatrice Terni et al.
BRAIN PATHOLOGY (2010)
The Alzheimer's Disease Mitochondrial Cascade Hypothesis
Russell H. Swerdlow et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Oxidative Balance in Alzheimer's Disease: Relationship to APOE, Braak Tangle Stage, and the Concentrations of Soluble and Insoluble Amyloid-beta
Hannah Tayler et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Abnormal morphology of peripheral cell tissues from patients with Huntington disease
Ferdinando Squitieri et al.
JOURNAL OF NEURAL TRANSMISSION (2010)
A Double-Blind, Placebo-Controlled Study to Assess the Mitochondria-Targeted Antioxidant MitoQ as a Disease-Modifying Therapy in Parkinson's Disease
Barry J. Snow et al.
MOVEMENT DISORDERS (2010)
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
Marta Martinez-Vicente et al.
NATURE NEUROSCIENCE (2010)
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction
Alberto Sanz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Injection of isolated mitochondria during early reperfusion for cardioprotection
James D. McCully et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Phase II Trial of CoQ10 for ALS Finds Insufficient Evidence to Justify Phase III
Petra Kaufmann et al.
ANNALS OF NEUROLOGY (2009)
Mitochondria Targeted Peptides Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Neurotoxicity
Lichuan Yang et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Oxidative Stress Involvement in α-Synuclein Oligomerization in Parkinson's Disease Cybrids
A. Raquel Esteves et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia
Weiping Qin et al.
ARCHIVES OF NEUROLOGY (2009)
How mitochondria produce reactive oxygen species
Michael P. Murphy
BIOCHEMICAL JOURNAL (2009)
Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease
Elke Hattingen et al.
BRAIN (2009)
Mitochondrial dynamics in Parkinson's disease
Victor S. Van Laar et al.
EXPERIMENTAL NEUROLOGY (2009)
Vitamin E Paradox in Alzheimer's Disease: It Does Not Prevent Loss of Cognition and May Even Be Detrimental
Ana Lloret et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
Xinglong Wang et al.
JOURNAL OF NEUROSCIENCE (2009)
PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-induced Cell Death
Sonia Gandhi et al.
MOLECULAR CELL (2009)
A novel NDUFA1 mutation leads to a progressive mitochondrial complex I-specific neurodegenerative disease
Prasanth Potluri et al.
MOLECULAR GENETICS AND METABOLISM (2009)
A highly reproducible rotenone model of Parkinson's disease
Jason R. Cannon et al.
NEUROBIOLOGY OF DISEASE (2009)
Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology
Robert E. Drolet et al.
NEUROBIOLOGY OF DISEASE (2009)
MAM: more than just a housekeeper
Teruo Hayashi et al.
TRENDS IN CELL BIOLOGY (2009)
The heritability and genetics of frontotemporal lobar degeneration
J. D. Rohrer et al.
NEUROLOGY (2009)
Why have antioxidants failed in clinical trials?
Steven R. Steinhubl
AMERICAN JOURNAL OF CARDIOLOGY (2008)
The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling
Anatoly A. Starkov
MITOCHONDRIA AND OXIDATIVE STRESS IN NEURODEGENERATIVE DISORDERS (2008)
A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria
Jan Trnka et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Protective effects of mitochondria-targeted antioxidant SkQ in aqueous and lipid membrane environments
Y. N. Antonenko et al.
JOURNAL OF MEMBRANE BIOLOGY (2008)
Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: Relevance to Alzheimer's disease
Wycliffe . Opii et al.
NEUROBIOLOGY OF AGING (2008)
Alzheimer's disease is associated with reduced expression of energy in posterior cingulate metabolism genes neurons
Winnie S. Liang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Functions and dysfunctions of mitochondrial dynamics
Scott A. Detmer et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Myelin breakdown and iron changes in Huntington's disease: Pathogenesis and treatment implications
George Bartzokis et al.
NEUROCHEMICAL RESEARCH (2007)
Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: Implications for the role of nitration in the progression of Alzheimer's disease
D. Allan Butterfield et al.
BRAIN RESEARCH (2007)
Mitochondria and neuronal activity
Oliver Kann et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Obligatory role for complex I inhibition in the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
Jason R. Richardson et al.
TOXICOLOGICAL SCIENCES (2007)
PGC-1α:: a key regulator of energy metabolism
Huiyun Liang et al.
ADVANCES IN PHYSIOLOGY EDUCATION (2006)
Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons:: implications for free radical generation and oxidative damage in disease progression
M Manczak et al.
HUMAN MOLECULAR GENETICS (2006)
Synaptic mitochondria are more susceptible to Ca2+ overload than nonsynaptic mitochondria
MR Brown et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Motor neuron disease in a patient with a mitochondrial tRNAIIe mutation
GM Borchwick et al.
ANNALS OF NEUROLOGY (2006)
Cholinesterase inhibitors for Alzheimer's disease
J Birks
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2006)
Normal huntingtin function: An alternative approach to Huntington's disease
E Cattaneo et al.
NATURE REVIEWS NEUROSCIENCE (2005)
DJ-1 mutations and parkinsonism-dementia-amyotrophic lateral sclerosis complex
G Annesi et al.
ANNALS OF NEUROLOGY (2005)
Ubiquitin immunohistochemistry suggests classic motor neuron disease, motor neuron disease with dementia, and frontotemporal dementia of the motor neuron disease type represent a clinicopathologic spectrum
IRA Mackenzie et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2005)
Ethyl-EPA in Huntington disease - A double-blind, randomized, placebo-controlled trial
BK Puri et al.
NEUROLOGY (2005)
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L Tau transgenic mice
DC David et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells
I Valle et al.
CARDIOVASCULAR RESEARCH (2005)
Frontotemporal lobar degeneration - Demographic characteristics of 353 patients
JK Johnson et al.
ARCHIVES OF NEUROLOGY (2005)
High dose vitamin E therapy in amyotrophic lateral sclerosis as add-on therapy to riluzole: results of a placebo-controlled double-blind study
M Graf et al.
JOURNAL OF NEURAL TRANSMISSION (2005)
Meta-analysis: High-dosage vitamin E supplementation may increase all-cause mortality
ER Miller et al.
ANNALS OF INTERNAL MEDICINE (2005)
Early Aβ accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain
M Ingelsson et al.
NEUROLOGY (2004)
A mitochondrial cascade hypthesis for sporadic Alzheimer's disease
RH Swerdlow et al.
MEDICAL HYPOTHESES (2004)
Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study
S Abrahams et al.
BRAIN (2004)
Frontotemporal lobar degeneration with motor neuron disease-type inclusions predominates in 76 cases of frontotemporal degeneration
AM Lipton et al.
ACTA NEUROPATHOLOGICA (2004)
Mechanism of toxicity in rotenone models of Parkinson's disease
TB Sherer et al.
JOURNAL OF NEUROSCIENCE (2003)
DJ-1 (PARK7), a novel gene for autosomal recessive, early onset parkinsonism
V Bonifati et al.
NEUROLOGICAL SCIENCES (2003)
A randomized sequential trial of creatine in amyotrophic lateral sclerosis
GJ Groeneveld et al.
ANNALS OF NEUROLOGY (2003)
Mitochondriopathy mimicking amyotrophic lateral sclerosis
J Finsterer
NEUROLOGIST (2003)
Wild-type huntingtin plays a role in brain development and neuronal survival
A Reiner et al.
MOLECULAR NEUROBIOLOGY (2003)
Unfolding the role of protein misfolding in neurodegenerative diseases
C Soto
NATURE REVIEWS NEUROSCIENCE (2003)
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part 1: Creatine kinase bb, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1
A Castegna et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Primary structure of a dynamin-related mouse mitochondrial GTPase and its distribution in brain, subcellular localization, and effect on mitochondrial morphology
T Misaka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
β-amyloid peptide induces ultrastructural changes in synaptosomes and potentiates mitochondrial dysfunction in the presence of ryanodine
X Mungarro-Menchaca et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
A randomised, placebo-controlled, double blind study of treatment of Huntington's disease with unsaturated fatty acids
KS Vaddadi et al.
NEUROREPORT (2002)
Positron emission tomography in evaluation of dementia - Regional brain metabolism and long-term outcome
DHS Silverman et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2001)
Oxidative damage is the earliest event in Alzheimer disease
A Nunomura et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)
Mitochondrial abnormalities in Alzheimer's disease
K Hirai et al.
JOURNAL OF NEUROSCIENCE (2001)
Selective targeting of a redox-active ubiquinone to mitochondria within cells - Antioxidant and antiapoptotic properties
GF Kelso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
R Betarbet et al.
NATURE NEUROSCIENCE (2000)
Abnormal mitochondrial morphology in sporadic Parkinson's and Alzheimer's disease cybrid cell lines
PA Trimmer et al.
EXPERIMENTAL NEUROLOGY (2000)