Can COVID-19 vaccines relieve severe tension-type headache and migraine?

Article Clinical Neurology

Latent class cluster analysis identified hidden headache phenotypes in COVID-19: impact of pulmonary infiltration and IL-6

Omer Karadas et al.

Summary: This study found that 28.9% of COVID-19 patients reported headache, with most of them having no prior history of headaches. Patients with headache showed higher frequency of pulmonary involvement and increased D-dimer levels. The characteristics and treatment response of the headaches were related to pulmonary involvement and IL-6 levels.

NEUROLOGICAL SCIENCES (2021)

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Article Clinical Neurology

Safety of anti-CGRP monoclonal antibodies in patients with migraine during the COVID-19 pandemic: Present and future implications

E. Caronna et al.

Summary: This study analyzed the impact of anti-CGRP monoclonal antibody (mAb) treatment on patients with migraine during the COVID-19 pandemic, and found that there was no association with increased risk of COVID-19. Patients treated with and without anti-CGRP mAbs showed no clinical differences during the pandemic.

NEUROLOGIA (2021)

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Review Immunology

The COVID-19 Vaccines: Recent Development, Challenges and Prospects

Yuxin Yan et al.

Summary: Developing COVID-19 vaccines is crucial for the world to return to pre-pandemic normalcy. Thirteen vaccines have been approved, with over 90 candidates in clinical trials. Despite being in its infancy, current progress in vaccine development is promising.

VACCINES (2021)

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Review Clinical Neurology

Diagnosis and management of migraine in ten steps

Anna K. Eigenbrodt et al.

Summary: Migraine is a common but often under-diagnosed and under-treated condition. The Consensus Statement provides guidelines for diagnosis and management, emphasizing the importance of patient education and patient-centered care.

NATURE REVIEWS NEUROLOGY (2021)

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Article Endocrinology & Metabolism

Circulating Levels of Calcitonin Gene-Related Peptide Are Lower in COVID-19 Patients

Laura Ochoa-Callejero et al.

Summary: The study revealed significantly decreased levels of CGRP in COVID-19 patients, with even lower levels in patients treated with proton pump inhibitors. Immunofluorescence showed RAMP1 activity in smooth muscle cells of blood vessels, airway epithelium, and proliferating type II pneumocytes in COVID-19 samples.

JOURNAL OF THE ENDOCRINE SOCIETY (2021)

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Article Clinical Neurology