Journal
MEDICAL HYPOTHESES
Volume 161, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.mehy.2022.110812
Keywords
COVID-19; Headache; Migraine; Vaccines
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This article presents 8 clinical cases of patients with chronic headache, in which the symptoms were completely or partially resolved after receiving COVID-19 vaccination. The administration of vaccines may inhibit the synthesis of pro-inflammatory cytokines, leading to an improvement or disappearance of symptoms in these patients.
Chronic headache is a frequent disorder that can cause a significant deterioration in the quality of life of the affected person. The COVID-19 pandemic is compelling all countries to develop a complete vaccination protocol for the entire population. In this article, we present 8 clinical cases of patients suffering chronic headache which resolved completely or partially after vaccination. Five patients had migraine, 2 had a post-viral headache typical of COVID-19, and one had a headache induced by sexual activity. Resolution was complete in 3 cases, almost complete in 2 others, and a great improvement was observed in the other 3. We hypothesize that the administration of vaccines for COVID-19 can produce an improvement or the disappearance of symptoms in our patients by inhibiting synthesis of pro-inflammatory cytokines.
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