Development of a QCM immunosensor with functionalized gold nanoparticles for the detection of Salmonella typhimurium

This study developed an immunosensor using the quartz crystal microbalance (QCM) to detect Salmonella typhimurium (S.typhimurium), using gold nanoparticles (AuNPs) as signal enhancers. The gold nanoparticles (AuNP) were functionalized with cysteinate and immobilized with a specific antibody to S.typhimurium (AbST). The previously treated gold nanoparticles were attached to the surface of the QCM for the detection of S. typhimurium. The effect of the gold nanoparticles size was explored to elucidate the optimal size as a signal enhancer.

Automated summary

This study developed an immunosensor using quartz crystal microbalance (QCM) to detect Salmonella typhimurium, with gold nanoparticles as signal enhancers. The effect of gold nanoparticle size was explored to determine the optimal size for enhancing the detection signal.