4.6 Article

Preparation of Au-based hybrid nanoflowers as efficient photothermal agents for antibacterial application

Journal

MATERIALS LETTERS
Volume 317, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.matlet.2022.132034

Keywords

Template approach; Au-based hybrid nanoflowers; Nanoparticles; Photothermal agent; Photothermal antibacterial; Biomaterials

Funding

  1. Hainan Provincial Natural Science Foundation of China [520QN225, 520QN224]
  2. Young Talents' Science and Technology Innovation Project of Hainan Association for Science and Technology [QCXM202030]

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In this study, hybrid nanoflowers composed of polydopamine and gold were constructed as photothermal agents. The resulting nanoflowers exhibited excellent stability and enhanced photothermal conversion ability. The antibacterial results showed effective antibacterial activity triggered by near-infrared stimulation.
In this study, hybrid nanoflowers (PDA@AuNFs) composed of polydopamine and gold were constructed as photothermal agents using a template approach. The key strategies are to use scaffolds as platforms for poly dopamine deposition and further modulate Au nanoparticle (AuNP) growth. The resultant PDA@AuNFs exhibited excellent stability and could overcome the shortcomings of nanoparticle aggregation. Furthermore, hybrid nanoflowers showed enhanced photothermal conversion ability, which is attributed to the broadband absorption, and multibranched structures. The photothermal antibacterial results suggest that with the temperature increasing from 45 degrees C to 55 degrees C, the antibacterial efficiency could reach 99%. These findings show that PDA@AuNFs triggered by near-infrared (NIR) exhibited effective antibacterial activity.

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