4.6 Article

Application of graphite carbon nitride in the field of biomedicine: Latest progress and challenges

Journal

MATERIALS CHEMISTRY AND PHYSICS
Volume 281, Issue -, Pages -

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.matchemphys.2022.125925

Keywords

G-C3N4; Biomedical applications; Biological imaging; PDT; Nanomedicine

Funding

  1. Natural Science Foundation of Jiangsu Province [BK20190909]
  2. High-level Innovation and EntrePreneurship Talents Introduction Program of Jiangsu Province of China
  3. Open Project of State Key Laboratory of Bioactive Substance and Function of natural Medicines [GTZK202008]

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Graphitic polymeric carbon nitride (g-C3N4), as a unique material with its unique element composition and photoelectric features, has attracted great interest in the field of biomedicine. g-C3N4, composed only of carbon and nitrogen, exhibits outstanding biocompatibility, making it suitable for applications in biological imaging, antibacterial materials, and photodynamic therapy. This review systematically examines the preparation methods of g-C3N4, its latest developments in biomedical applications, and discusses its biological safety, challenges, and prospects. It is expected that g-C3N4 will be recognized for clinical applications in the near future.
As a new type of graphene-like material, graphitic polymeric carbon nitride (g-C3N4) has gradually attracted great interest in the field of biomedicine due to their unique element composition and photoelectric features. g-C3N4 composed only of carbon and nitrogen has outstanding biocompatibility, which was beneficial to the application in the field of biomedicine. The fluorescent characteristics of g-C3N4 can be applied to biological imaging. Furthermore, its appropriate energy level (2.7 eV) can promote the deposition of electrons, making g-C3N4 useful for antibacterial materials and photodynamic therapy (PDT). In this manuscript, we systematically reviewed the preparation methods of g-C3N4 and its latest developments in biomedical applications, and the biological safety of g-C3N4 is discussed in-depth. The challenges and prospects of g-C3N4 in biology and medicines are also discussed in detail. It is foreseeable that the emerging g-C3N4 will be recognized the clinical applications in the near future.

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