Journal
JOURNAL OF ULTRASOUND IN MEDICINE
Volume 42, Issue 1, Pages 7-15Publisher
WILEY
DOI: 10.1002/jum.15988
Keywords
fallopian tube patency tests; hysterosalpingography; infertility; SonoVue; ultrasonography
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This study aimed to evaluate the diagnostic value of HyCoSy using sulfur hexafluoride microbubbles for fallopian tubal patency assessment in infertile females. The results showed that the sensitivity of HyCoSy was 93%, while the specificity was 90%, indicating a high accuracy in diagnosing fallopian tube patency.
This study aimed to evaluate the diagnostic value of HyCoSy using sulfur hexafluoride microbubbles for fallopian tubal patency assessment in infertile females. Twenty-four studies, including 1358 females with 2661 detected fallopian tubes published from January 2003 to May 2019, were identified. The pooled sensitivity was 93% (95% CI: 90-95%), while the specificity was 90% (95% CI: 87-92%). The area under the receiver-operating characteristic curve was 0.96 (95% CI: 94-98%). The specificity of the four-dimensional HyCoSy subgroup was higher than the 2D/3D subgroup; an increased dose of contrast agent did not affect the specificity, with only a slightly reduced sensitivity.
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