Journal
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
Volume 30, Issue 17, Pages E1084-E1094Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.5435/JAAOS-D-21-01155
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This article provides a broad overview, mechanism of action, and evidence behind various intradiscal therapies for discogenic low back pain. While some non-surgical treatments are still in the clinical trial stage, there is limited evidence for many of these techniques.
Discogenic low back pain is a common musculoskeletal complaint in patients presenting to orthopaedic surgeons. In addition to surgical options, there are several nonsurgical intradiscal treatments that have gained interest, ranging from biologic, nonbiologic, cell-based, and molecular therapies. However, there is limited evidence for many of these techniques, and some are still in the clinical trial stage. We describe a broad overview of these intradiscal therapies, the mechanism of action, and the evidence behind them.
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