4.3 Article

Development of PHITS graphical user interface for simulation of positron emitting radioisotopes production in common biological materials during proton therapy

Journal

JOURNAL OF RADIATION RESEARCH
Volume 63, Issue 3, Pages 385-392

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/jrr/rrac010

Keywords

Monte Carlo (MC); nuclear radiation; Particle and Heavy Ion Transport Code System (PHITS); positron; proton therapy

Funding

  1. Special Grant for the Development of Virtual Teaching and Learning (VTL) from the University Grants Committee of Hong Kong SAR [6430120]
  2. Agency for Medical Research and Development (AMED) [20he2202004h0402]

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The Monte Carlo method is a powerful tool for modeling nuclear radiation interaction with matter. In this study, a custom-made GUI bundled with a 3D OpenGL visualizer has been developed for the PHITS MC package. The program focuses on modeling proton induced positron emitting radioisotopes, which can be used for verifying proton ranges in proton therapy. The GUI program is user-friendly and distributed under an open-source license.
The Monte Carlo (MC) method is a powerful tool for modeling nuclear radiation interaction with matter. A variety of MC software packages has been developed, especially for applications in radiation therapy. Most widely used MC packages require users to write their own input scripts for their systems, which can be a time consuming and error prone process and requires extensive user experience. In the present work, we have developed a graphical user interface (GUI) bundled with a custom-made 3D OpenGL visualizer for PHITS MC package. The current version focuses on modeling proton induced positron emitting radioisotopes, which in turn can be used for verification of proton ranges in proton therapy. The developed GUI program does not require extensive user experience. The present open-source program is distributed under GPLv3 license that allows users to freely download, modify, recompile and redistribute the program.

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