Effects of endovascular therapy for mild stroke due to proximal or M2 occlusions: meta-analysis

Article Medicine, General & Internal

Endovascular Therapy for Acute Stroke with a Large Ischemic Region

S. Yoshimura et al.

Summary: In a trial conducted in Japan, patients with large cerebral infarctions had better functional outcomes with endovascular therapy than with medical care alone but had more intracranial hemorrhages.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Review Neuroimaging

More expansive horizons: a review of endovascular therapy for patients with low NIHSS scores

David J. McCarthy et al.

Summary: The efficacy of EVT for patients with low NIHSS scores remains uncertain, with significant heterogeneity and inconclusive results in existing literature. Future randomized clinical trials are needed to better understand the potential benefit of EVT in this patient population.

JOURNAL OF NEUROINTERVENTIONAL SURGERY (2021)

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Article Clinical Neurology

Treatment and Outcome in Stroke Patients With Acute M2 Occlusion and Minor Neurological Deficits

Tomas Dobrocky et al.

Summary: This study compared the outcomes of intravenous thrombolysis (IVT) with endovascular therapy (EVT) (+/- IVT) and IVT with mechanical thrombectomy (MT) in patients with peripheral middle cerebral artery occlusions and minor neurological deficits. The results showed similar effectiveness between IVT and EVT, as well as IVT and MT, in these patients, with a potential benefit of EVT in those treated after 2015.

STROKE (2021)

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Article Clinical Neurology

Prediction of Early Neurological Deterioration in Individuals With Minor Stroke and Large Vessel Occlusion Intended for Intravenous Thrombolysis Alone

Pierre Seners et al.

Summary: The study aimed to develop and validate an easily applicable predictive score for early neurological deterioration following intravenous thrombolysis in patients with acute minor stroke and large vessel occlusion. The results showed that a score based on thrombus length and occlusion site had good discriminative power for identifying ENDi risk, with higher scores associated with greater probability of ENDi occurring.

JAMA NEUROLOGY (2021)

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Article Clinical Neurology

Perfusion and Diffusion Variables Predict Early Neurological Deterioration in Minor Stroke and Large Vessel Occlusion

Dong-Seok Gwak et al.

Summary: This study identified Tmax >6 seconds, Tmax >6 seconds - DWI, and Tmax 4-6 seconds as the optimal imaging variables for predicting early neurological deterioration in patients with mild stroke due to large vessel occlusion, independently associated with an increased risk of END.

JOURNAL OF STROKE (2021)

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Article Clinical Neurology

Middle Cerebral Artery M2 Thrombectomy in the STRATIS Registry

Mouhammad A. Jumaa et al.

Summary: In the STRATIS Registry, patients with M2 occlusions achieved similar rates of successful reperfusion, good functional outcome, and mortality compared to M1 occlusions, although there were increased rates of symptomatic intracranial hemorrhage in the M2 group. Further studies are needed to understand the benefits of mechanical thrombectomy for M2 occlusions.

STROKE (2021)

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Review Clinical Neurology