4.4 Article

A feruloylated acylglycerol isolated from Wikstroemia pilosa and its distribution in ten plants of Wikstroemia species

Journal

JOURNAL OF NATURAL MEDICINES
Volume 76, Issue 3, Pages 680-685

Publisher

SPRINGER JAPAN KK
DOI: 10.1007/s11418-022-01621-6

Keywords

Feruloylated acylglycerol; Wikstroemia pilosa; Wikstroemia; LC-MS

Funding

  1. Japan Society for the Promotion of Science KAKENHI [21K06619]
  2. Grants-in-Aid for Scientific Research [21K06619] Funding Source: KAKEN

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A novel feruloylated acylglycerol derivative was isolated from Wikstroemia pilosa, and its structure was determined through extensive physiochemical and spectroscopic analysis. The contents of the derivative in ten Wikstroemia species were quantitatively analyzed using high-resolution accurate mass LC-MS.
Feruloylated acylglycerols (FAGs) have recently garnered a lot of interest as water-oil-miscible ferulic acid derivatives. A novel FAG derivate, 1-feruloyl-3-hexadecanoylglycerol (1), was isolated from Wikstroemia pilosa and its structure was elucidated from extensive physiochemical and spectroscopic analysis. Since the limited distribution of FAGs in plant species has been reported, a high-resolution accurate mass (HRAM) LC-MS quantitative analysis was carried out to determine the contents of 1 in ten plants of Wikstroemia species. As a result, compound 1 was detected in all species at contents of 1.29-50.96 mg/kg dry weight and W. dolichantha contained 1 at the highest content.

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