4.8 Editorial Material

When One Mutation Is All It Takes

Journal

CANCER CELL
Volume 27, Issue 4, Pages 433-434

Publisher

CELL PRESS
DOI: 10.1016/j.ccell.2015.03.016

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Funding

  1. Wellcome Trust [105104] Funding Source: Medline

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In a recent issue of Nature Genetics, Andersson and colleagues report that MLL fusion alone may be sufficient to spawn an aggressive leukemia in infants. Some other pediatric cancers may share a similar, single, big-hit'' origin, possibly reflecting a critical developmental window of stem cell vulnerability.

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