4.8 Editorial Material

Immunotherapy Not Working? Check Your Microbiota

Journal

CANCER CELL
Volume 28, Issue 6, Pages 687-689

Publisher

CELL PRESS
DOI: 10.1016/j.ccell.2015.11.010

Keywords

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Funding

  1. Wellcome Trust [095688] Funding Source: Medline
  2. Wellcome Trust [095688/Z/11/Z] Funding Source: Wellcome Trust
  3. BBSRC [BB/I005609/1] Funding Source: UKRI
  4. Biotechnology and Biological Sciences Research Council [BB/I005609/1] Funding Source: researchfish
  5. Wellcome Trust [095688/Z/11/Z] Funding Source: researchfish

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Gut microbes have ascended to prominence as key modulators of host immunity, raising the possibility that they could influence the outcome of cancer immunotherapy. Two recent studies address this question by identifying specific gut-resident bacteria as drivers of checkpoint blockade immunotherapy in pre-clinical tumor models.

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