Journal
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
Volume 50, Issue 2, Pages -Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/03000605211059933
Keywords
Lance Adams syndrome; levetiracetam; case report
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This case report describes two patients with hypoxic myoclonus, who showed significant improvement in neurological symptoms after the administration of clonazepam and sodium valproate sustained-release tablets. The article also presents a literature review on the pathogenesis, diagnosis, and treatment of Lance Adams syndrome.
Hypoxic myoclonus, also known as Lance Adams syndrome, is a rare syndrome that results from the serious brain damage caused by cerebral hypoxia that often follows cardiopulmonary resuscitation. This current case report describes two patients with post-hypoxic myoclonus, both of whom received cardiopulmonary resuscitation. The neurological symptoms of these two patients were significantly improved by the administration of clonazepam and sodium valproate sustained-release tablets. The report presents a literature review detailing the pathogenesis, diagnosis and treatment of Lance Adams syndrome. The timely diagnosis and treatment of Lance Adams syndrome can significantly improve the quality of life of patients. Valproic acid, clonazepam and other antiepileptic drugs can be used. Whether levetiracetam is effective for cortical myoclonus requires further clinical study.
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