Journal
JOURNAL OF HUMAN HYPERTENSION
Volume 36, Issue 11, Pages 952-959Publisher
SPRINGERNATURE
DOI: 10.1038/s41371-022-00698-6
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Funding
- Fogarty International Center of the National Institutes of Health [D43 TW009744, D43 TW009337, K01HL130497, R03HL155041, R01HL144941]
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This article explores the relationship between gut microbiota composition and cardiovascular diseases, as well as their association with CVD risk factors. It also mentions potential therapies for improving gut microbiota composition that may have positive effects on cardiovascular health.
The gut microbiota has recently gained attention due to its association with cardiovascular health, cancers, gastrointestinal disorders, and non-communicable diseases. One critical question is how the composition of the microbiota contributes to cardiovascular diseases (CVDs). Insightful reviews on the gut microbiota, its metabolites and the mechanisms that underlie its contribution to CVD are limited. Hence, the aim of this review was to describe linkages between the composition of the microbiota and CVD, CVD risk factors such as hypertension, diet, ageing, and sex differences. We have also highlighted potential therapies for improving the composition of the gut microbiota, which may result in better cardiovascular health.
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