Effectiveness of ultraviolet-C vs aerosolized hydrogen peroxide in ICU terminal disinfection

Background: According to the Centers for Disease Control and Prevention, 10% of patients with healthcare-acquired infections (HAIs) died during hospitalization in 2015. Thus, a reduction in the prevalence of HAIs is critical. One strategy to achieve this is the adequate disinfection of patient rooms within hospitals. Aim: To compare the effectiveness of an ultraviolet-C (UV-C) room sanitizer with an aerosolized hydrogen peroxide (aHP) device for the elimination of selected healthcareassociated (HA) pathogens and other HA organisms in an intensive care unit (ICU) setting. Methods: The disinfection systems were tested on the following organisms: meticillinresistant Staphylococcus aureus, extended-spectrum beta-lactamase-producing Klebococci, multi-drug-resistant Acinetobacter baumannii and Candida auris. Media plates with known densities of each organism were placed at preselected regions within an ICU room. The mean kill rate was determined for each organism. Additionally, swabs were taken from five high-touch areas from different ICU rooms prior to manual cleaning, following manual cleaning, and following each disinfection method in order to compare their effectiveness. Findings: The UV-C device achieved a 96.75% mean microbial reduction in non-shaded areas. It was significantly less effective in shaded areas. The aHP system achieved a mean kill rate of 50.71% for all areas. The swab results revealed that 15% of manually cleaned surfaces still harboured a microbial load, which was eradicated after use of either of the no-touch disinfection systems. Conclusion: This study found notable differences between two no-touch disinfection methods, highlights their effectiveness, and advocates for their incorporation alongside a manual cleaning regimen. (c) 2021 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Automated summary

This study compared the effectiveness of two no-touch disinfection methods in eliminating healthcareassociated pathogens and other organisms in an intensive care unit (ICU) setting. The UV-C room sanitizer achieved a higher microbial reduction rate in non-shaded areas compared to the aerosolized hydrogen peroxide (aHP) device. After manual cleaning, 15% of surfaces still harbored microbial load, but this was eradicated when the no-touch disinfection systems were used.