Journal
JOURNAL OF HEPATOLOGY
Volume 76, Issue 6, Pages 1318-1329Publisher
ELSEVIER
DOI: 10.1016/j.jhep.2022.03.003
Keywords
Prognostication; Allocation; Frailty; Sarcopenia; EHR; OMOP; Clinical Decision Support
Categories
Funding
- AASLD Anna S. Lok Advanced/Transplant Hepatol-ogy Award (AASLD Foundation) [R01DK127224]
- National Institute of Diabetes and Digestive and Kidney Diseases, Kim
- National Institute on Aging, Lai [R01AG059183]
- Clinical, Translational, and Outcomes Research Award (AASLD Foundation, Kwong)
- National Institute on Alcohol Abuse and Alcoholism, Kwong [K23AA029197]
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This review article discusses the model for end-stage liver disease (MELD) score and its dual purpose in general and transplant hepatology. The article summarizes emerging concepts, methodologies, and technologies that may improve mortality prognostication in the future, and explores how these novel concepts and technologies may be incorporated into clinical practice.
In this review article, we discuss the model for end-stage liver disease (MELD) score and its dual purpose in general and transplant hepatology. As the landscape of liver disease and transplantation has evolved considerably since the advent of the MELD score, we summarise emerging concepts, methodologies, and technologies that may improve mortality prognostication in the future. Finally, we explore how these novel concepts and technologies may be incorporated into clinical practice. (C) 2022 Published by Elsevier B.V. on behalf of European Association for the Study of the Liver.
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