EASL Clinical Practice Guidelines on prevention and management of bleeding and thrombosis in patients with cirrhosis

The prevention and management of bleeding and thrombosis in patients with cirrhosis poses several difficult clinical questions. These Clinical Practice Guidelines have been developed to provide practical guidance on debated topics, including current views on haemostasis in liver disease, controversy regarding the need to correct thrombocytopenia and abnormalities in the coagulation system in patients undergoing invasive procedures, and the need for thromboprophylaxis in hospitalised patients with haemostatic abnormalities. Multiple recommendations in this document are based on interventions that the panel feels are not useful, even though widely applied in clinical practice. (C) 2021 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

Automated summary

This article discusses the challenging issues of bleeding and thrombosis prevention and management in patients with cirrhosis, providing practical guidance. Some recommendations in this document are based on the panel's view that certain commonly used interventions are not useful.